N. D. Youngblut

Medication Use is Associated with Distinct Microbial Features in Anxiety and Depression

This study links medication use to distinct gut microbial features in anxiety and depression, showing antidepressants have a larger effect on microbiota than diagnoses.

An integrated systems-biology platform for power-to-gas technology

This paper develops a systems-biology platform for Methanothermobacter spp. to optimize power-to-gas technology by analyzing genome-scale metabolic models and growth performance in bioreactors.

Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5

The paper identifies a novel mechanism of TLR5 interaction with flagellins from gut commensal bacteria, termed silent recognition, which explains weak immune responses despite strong binding.

Tracing carbon metabolism with stable isotope metabolomics reveals the legacy of diverse carbon sources in soil

This study uses stable isotope metabolomics to track 13C from diverse carbon sources in soil over time, showing that carbon source type influences metabolite labeling and microbial activity patterns.

Bacterial community dynamics explain carbon mineralization and assimilation in soils of different land-use history

The paper links bacterial community dynamics to carbon mineralization and assimilation in soils with different land-use histories using DNA-stable isotope probing.

Codiversification of gut microbiota with humans

The paper identifies gut microbes that codiversified with human populations, showing vertical transmission and potential population-specific health benefits.

Multi-substrate DNA stable isotope probing reveals guild structure in bacterially mediated soil carbon cycling

The paper uses multi-substrate DNA stable isotope probing to identify bacterial guilds in soil carbon cycling, showing that C source bioavailability and guild structure influence C mineralization and biogeography.

Strong influence of vertebrate host phylogeny on gut archaeal diversity

This study investigates the influence of vertebrate host phylogeny on gut archaeal diversity using 16S rRNA sequencing, finding that host phylogeny explains diversity more than diet.

Free-living psychrophilic bacteria of the genus Psychrobacter are descendents of pathobionts

This study shows Psychrobacter evolved from warm-adapted pathobionts, with some losing the ability to grow at 37°C and adapting to cold environments.

Reclassification of Catabacter hongkongensis as Christensenella hongkongensis comb.nov. based on whole genome analysis

The paper reclassifies Catabacter hongkongensis into the genus Christensenella based on whole-genome analysis showing it belongs to the Christensenella clade.

Genomic insights into adaptations of TMA-utilizing methanogens to diverse habitats including the human gut

This study analyzes Methanomassiliicoccales genomes and metagenomes to understand their adaptation to diverse habitats, including the human gut, and their association with trimethylamine-producing bacteria.

Strain-level analysis of Bifidobacterium spp. from gut microbiomes of adults of differing lactase persistence genotypes

This study analyzes Bifidobacterium strains in gut microbiomes of adults with different lactase persistence genotypes, finding no effect of LCT genotype on strain composition but intra-individual stability and twin-related strain sharing.

Large scale metagenome assembly reveals novel animal-associated microbial genomes, biosynthetic gene clusters, and other genetic diversity

The paper performs large-scale metagenome assembly of animal gut microbiomes, revealing novel microbial genomes, biosynthetic gene clusters, and genetic diversity across vertebrates.

Syntrophy via interspecies H2 transfer between Christensenella and Methanobrevibacter underlies their global co-occurrence in the human gut

The paper shows that Christensenella and Methanobrevibacter species co-occur in the human gut due to interspecies H2 transfer, supporting a lean BMI association through metabolic interactions.

Host diet and evolutionary history explain different aspects of gut microbiome diversity among vertebrate clades

The paper examines how host evolutionary history and diet influence gut microbiome diversity across vertebrate clades using a large dataset of wild animals.