Author

N. H. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:development & morphogenesis· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Assay:proteomics· 2

Frequent Co-Authors

J. J. Choi· 4 shared M. Mohiuddin· 4 shared W. M. Han· 4 shared Y. C. Jang· 4 shared S. E. Anderson· 3 shared B. Aliya· 2 shared C. A. Aguilar· 2 shared E. J. Shin· 2 shared

Activity by Year

2018-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersCell Biology

J. J. Choi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Regenerating motor neurons prime muscle stem cells for myogenesis by enhancing protein synthesis and mitochondrial bioenergetics

J. J. Choi, E. J. Shin, W. M. Han, S. E. Anderson, M. Mohiuddin, N. H. Lee, T. Tran, S. Nakhai, H. Jeong, A. Shcherbina, G. Jeong, D. G. Oh, L. Weinstock, S. B. Sankar, M. E. Ogle, , Y. C. Jang

This study shows that motor neurons enhance muscle stem cell function by boosting protein synthesis and mitochondrial activity, which is critical for muscle regeneration and is disrupted in diseases like muscular dystrophy and aging.

bioRxiv · May 24, 2020 · PreprintCell Biology

Transplantation of muscle stem cell mitochondria rejuvenates the bioenergetic function of dystrophic muscle

M. Mohiuddin, J. J. Choi, N. H. Lee, H. H. Jeong, S. E. Anderson, W. M. Han, B. Aliya, T. Z. Peykova, S. Verma, A. J. Garcia, C. A. Aguilar, Y. C. Jang

This study shows that transplanting healthy muscle stem cells into dystrophic muscle improves mitochondrial function and bioenergetics, while compromised stem cells fail to do so.

bioRxiv · Apr 17, 2020 · PreprintCell Biology

Engineered Heterochronic Parabiosis in 3D Microphysiological System for Identification of Muscle Rejuvenating Factors

Y. Lee, J. J. Choi, S. I. Ahn, N. H. Lee, W. M. Han, M. Mohiuddin, E. J. Shin, L. B. Wood, K. D. Park, Y. Kim, Y. C. Jang

This study develops an in vitro muscle parabiosis system to identify rejuvenating factors in aged muscle stem cells by mimicking systemic and local signals.

bioRxiv · Mar 10, 2020Cell Biology

Critical Limb Ischemia Induces Remodeling of Skeletal Muscle Motor Unit and Myonuclear- and Mitochondrial-Domains

M. Mohiuddin, N. H. Lee, J. Y. Moon, W. M. Han, S. E. Anderson, J. J. Choi, S. Nakhai, T. Tran, B. Aliya, D. Y. Kim, A. Gerold, L. Hansen, W. R. Taylor, Y. C. Jang

This study investigates how critical limb ischemia affects skeletal muscle by increasing myonuclear number and mitochondrial content per myonucleus in mice.

bioRxiv · Sep 25, 2018Physiology