Author

D. Aguilar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

A. C. Ramon· 2 shared E. Caballero· 2 shared G. V. Perez· 2 shared M. Rosales· 2 shared S. E. Perea· 2 shared Y. Ke· 2 shared Y. Perera· 2 shared Y. Ramos· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. C. Ramon

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Sensory neurons regulate stimulus-dependent humoral immunity

D. Aguilar, F. Zhu, A. Millet, N. Millet, P. Germano, J. Pisegna, O. Akbari, T. A. Doherty, M. Swidergall, N. Jendzjowsky

This study shows sensory neurons regulate humoral immunity by releasing neuropeptides that influence B-cell responses and antibody production in bacterial infection and allergic asthma.

bioRxiv · Jan 4, 2024 · PreprintImmunology

Circulating tumor extracellular vesicles to monitor metastatic prostate cancer genomics and transcriptomic evolution

I. Casanova-Salas, S. Cordoba-Terreros, D. Aguilar, L. Agundez, J. Brandariz, N. Herranz, M. Gonzalez, R. Morales-Barrera, A. Sierra, M. Soriano-Navarro, P. Cresta, S. Simonetti, G. Rodrigues, S. Arce-Gallego, L. Delgado, , J. Mateo

This study shows that circulating tumor extracellular vesicles can be used to monitor genomic and transcriptomic changes in metastatic prostate cancer through liquid biopsy.

bioRxiv · Apr 14, 2023Cancer Biology

Macrophage and neutrophil heterogeneity at single-cell spatial resolution in inflammatory bowel disease

A. Garrido-Trigo, A. Corraliza, M. Veny, I. Dotti, E. Melon-Ardanaz, A. Rill, H. L. Crowell, A. Corbi, V. Gudino, M. Esteller, I. Alvarez-Teubel, D. Aguilar, M. C. Masamunt, E. Killingbeck, Y. Kim, , A. Salas

The paper identifies macrophage and neutrophil heterogeneity in inflammatory bowel disease using single-cell and spatial transcriptomics, revealing distinct subtypes and their potential roles in disease.

bioRxiv · Nov 28, 2022 · PreprintImmunology

Targeting of Protein Kinase CK2 Elicits Antiviral Activity on Bovine Coronavirus Infection

A. C. Ramon, G. V. Perez, E. Caballero, M. Rosales, D. Aguilar, D. M. Vazquez-Blomquist, Y. Ramos, A. Rodriguez, V. Falcon, M. P. Rodriguez, Y. Ke, Y. Perera, S. E. Perea

This study shows that CIGB-325, an anti-CK2 peptide, inhibits bovine coronavirus infection by reducing viral protein accumulation and cytopathic effects.

bioRxiv · Jun 8, 2021Pharmacology & Toxicology

Targeting of Protein Kinase CK2 in Acute Myeloid Leukemia Cells Using the Clinical-Grade Synthetic-Peptide CIGB-300

M. Rosales, G. V. Perez, A. C. Ramon, Y. Cruz, A. Rodriguez-Ulloa, V. Besada, Y. Ramos, D. Vazquez-Blomquist, E. Caballero, D. Aguilar, L. J. Gonzalez, K. Zettl, J. R. Wisniewski, Y. Ke, Y. Perera, S. E. Perea

This study investigates the anti-proliferative and proapoptotic effects of the CK2 inhibitor CIGB-300 on AML cells and identifies its molecular targets.

bioRxiv · May 19, 2021Cancer Biology