Author

V. F. Vartabedian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

J. R. Teijaro· 3 shared A. J. Thompson· 1 shared A. Torkamani· 1 shared C. Kikuchi· 1 shared D. C. Lazar· 1 shared D. W. Wolan· 1 shared D.-E. Zhang· 1 shared J. C. Paulson· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersImmunology

J. R. Teijaro

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3 papers

Recent·Most cited

Sialic acid ligands of CD28 block co-stimulation of T cells

L. J. Edgar, A. J. Thompson, V. F. Vartabedian, C. Kikuchi, J. L. Woehl, J. R. Teijaro, J. C. Paulson

The paper shows sialic acid ligands on T cells and APCs block CD28 co-stimulation, reducing T cell activation and enhancing effector function when sialic acids are removed.

bioRxiv · Feb 22, 2021 · PreprintImmunology

Identification of an N-acetylneuraminic acid-presenting bacteria isolated from a healthy human microbiome

Z. Han, P. S. Thuy-Boun, W. Pfeiffer, V. F. Vartabedian, A. Torkamani, J. R. Teijaro, D. W. Wolan

The paper identifies an Escherichia coli strain that presents sialic acid on its surface and develops a method to track sialic acid-presenting microbes in complex microbiomes.

bioRxiv · Aug 24, 2020Microbiology

ISG15 drives immune pathology and respiratory failure during viral infection

N. Shaabani, J. Zak, J. L. Johnson, Z. Huang, N. Nguyen, D. C. Lazar, V. F. Vartabedian, N. Honke, M. Prinz, K.-P. Knobeloch, K.-i. Arimoto, D.-E. Zhang, S. D. Catz, J. R. Teijaro

This study shows that lack of deISGylation during viral infection leads to immune pathology and respiratory failure, with extracellular ISG15 playing a key role in inflammation and disease severity.

bioRxiv · Apr 13, 2020 · PreprintImmunology