Helminth exposure protects against murine SARS-CoV-2 infection through macrophage dependent T cell activation
K. L. Hilligan, O. O. Oyesola, S. Namasivayam, N. Howard, C. S. Clancy, S. D. Oland, N. L. Garza, B. A. P. Lafont, R. F. Johnson, K. D. Mayer-Barber, A. Sher, P. Loke
This study shows that prior helminth infection reduces SARS-CoV-2 viral loads in mice by enhancing CD8+ T cell responses through macrophage-dependent mechanisms.
bioRxiv · Nov 9, 2022 · PreprintImmunology