Author

N. J. Haradhvala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

G. Getz· 2 shared A. Boot· 1 shared A. Dutta· 1 shared A. Langenbucher· 1 shared A. W. T. Ng· 1 shared B. Berrios· 1 shared B. T. Nicholson· 1 shared C. Tiedje· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

G. Getz

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Author profile →

3 papers

Recent·Most cited

Systematic characterization of therapeutic vulnerabilities in Multiple Myeloma with Amp1q reveals increased sensitivity to the combination of MCL1 and PI3K inhibitors

R. Sklavenitis-Pistofidis, E. D. Lightbody, M. Reidy, J. Tsuji, M. P. Aranha, D. Heilpern-Mallory, D. Huynh, S. J. F. Chong, L. Hackett, N. J. Haradhvala, T. Wu, N. K. Su, B. Berrios, J.-B. Alberge, A. Dutta, , S. Manier

bioRxiv · Aug 1, 2023 · PreprintCancer Biology

The Repertoire of Mutational Signatures in Human Cancer

L. Alexandrov, J. Kim, N. J. Haradhvala, M. N. Huang, A. W. T. Ng, Y. Wu, A. Boot, K. R. Covington, D. A. Gordenin, E. Bergstrom, S. M. A. Islam, N. Lopez-Bigas, L. J. Klimczak, J. R. McPherson, S. Morganella, , M. R. Stratton

The paper characterizes 49 mutational signatures in human cancer using a large dataset of somatic mutations, revealing associations with exposures and DNA repair mechanisms and identifying signatures of unknown origin.

bioRxiv · Jul 3, 2019Cancer Biology

A post-transcriptional program of chemoresistance by AU-rich elements and TTP

S. Lee, D. Micalizzi, S. S. Truesdell, S. I. Bukhari, M. Boukhali, J. Lombardi-Story, Y. Kato, I. Dey-Guha, B. T. Nicholson, M.-K. Choo, D. T. Myers, D. Lee, M. A. Mazzola, R. Raheja, A. Langenbucher, , S. Vasudevan

This study identifies a post-transcriptional mechanism of chemoresistance in leukemia involving AU-rich elements and TTP regulation.

bioRxiv · May 3, 2019 · PreprintCancer Biology