Author

J. Keiser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

J. Dommann· 2 shared P. Schneeberger· 2 shared A. Au· 1 shared A. E. Marriott· 1 shared A. Egli· 1 shared A. Gandelin· 1 shared A. J. Russell· 1 shared A. R. Burns· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersMicrobiology

J. Dommann

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A novel barcoded nanopore sequencing workflow of high-quality, full-length bacterial 16S amplicons for taxonomic annotation of bacterial isolates and complex microbial communities

J. Dommann, J. Kerbl-Knapp, D. Albertos Torres, A. Egli, J. Keiser, P. Schneeberger

This paper introduces a nanopore sequencing workflow for high-quality, full-length 16S rDNA amplicons to identify bacterial isolates and profile microbial communities, showing high agreement with MALDI-TOF and strong correlation with Illumina sequencing.

bioRxiv · Apr 11, 2024Microbiology

Exposure of gut bacterial isolates to the anthelminthic drugs, ivermectin and moxidectin, leads to antibiotic-like phenotypes of growth inhibition and adaptation.

J. Dommann, J. Keiser, J. Garneau, A. Gandelin, C. Casanova, P. M. Keller, S. Sayasone, P. Vonaesch, P. Schneeberger

This study shows that ivermectin and moxidectin inhibit gut bacterial growth and induce antibiotic-like resistance, raising concerns about cross-resistance to other antibiotics.

bioRxiv · Jan 17, 2024Microbiology

Nementin is a Nematode-Selective Small Molecule Agonist of Neurotransmitter Release

S. Harrington, J. J. Knox, A. R. Burns, K.-L. Choo, A. Au, M. Kitner, C. Haeberli, J. Pyche, C. D'Amata, Y.-H. Kim, J. Volpatti, M. Guiliani, J. Snider, V. Wong, B. M. Palmeira, , P. Roy

A C. elegans-based screening pipeline identifies a selective nematicide that also potentiates acetylcholinesterase inhibitors.

bioRxiv · Mar 12, 2022 · PreprintPharmacology & Toxicology

Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites - Trichuris muris, Brugia malayi, Heligmosomoides polygyrus and Schistosoma mansoni

F. A. Partridge, C. J. Bataille, R. Forman, A. E. Marriott, J. Forde-Thomas, C. Häberli, R. L. Dinsdale, J. D. O'Sullivan, N. J. Willis, G. M. Wynne, H. Whiteland, J. Archer, A. Steven, J. D. Turner, J. Keiser, , D. B. Sattelle

The paper investigates the structure-activity relationship of dihydrobenzoxazepinone (DHB) compounds against various parasitic nematodes and trematodes, identifying key structural features for anthelmintic activity.

bioRxiv · Nov 17, 2020Pharmacology & Toxicology