Author

N. Kotani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

T. Nakano· 4 shared R. Kuwahara· 3 shared T. Murakoshi· 3 shared K. Honke· 2 shared Y. Ida· 2 shared Y. Nakano· 2 shared A. Shimada· 1 shared A. Yamaguchi· 1 shared

Activity by Year

2018-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

T. Nakano

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Screening of candidate host cell membrane proteins involved in SARS-CoV-2 entry

N. Kotani, T. Nakano, R. Kuwahara

The paper identifies host cell membrane proteins that co-localize with SARS-CoV-2 spike proteins and show enhanced viral infectivity, suggesting potential roles in viral entry.

bioRxiv · Sep 9, 2020 · PreprintBiochemistry

Bimolecule detection for Extracellular Vesicle Screening

H. Kaneda, Y. Ida, R. Kuwahara, I. Sato, T. Nakano, H. Tokuda, T. Sato, T. Murakoshi, K. Honke, N. Kotani

The paper introduces a novel BiEV method to detect specific bimolecular surface antigens on extracellular vesicles for cancer screening, identifying CHL1-SLC4A1 and CHL1-caspase 14 as potential biomarkers in mouse and human samples.

bioRxiv · Jul 23, 2020 · PreprintBiochemistry

NPC1L1 inhibition disturbs lipid trafficking and induces large lipid droplet formation in intestinal absorptive epithelial cells

T. Nakano, I. Inoue, Y. Takenaka, R. Ito, N. Kotani, S. Sato, Y. Nakano, M. Hirasaki, A. Shimada, T. Murakoshi

This study shows that NPC1L1 inhibition reduces chylomicron assembly and secretion in intestinal cells by limiting cholesterol availability, leading to large lipid droplet formation.

bioRxiv · Apr 17, 2020Biochemistry

Proximity proteomics identifies cancer cell membrane cis-molecular complex as a potential cancer target

N. Kotani, A. Yamaguchi, T. Ohnishi, R. Kuwahara, T. Nakano, Y. Nakano, Y. Ida, T. Murakoshi, K. Honke

The paper identifies cancer cell membrane cis-molecular complexes (BiCATs) as potential targets using proximity proteomics and shows their utility in combination drug strategies.

bioRxiv · Oct 29, 2018Biochemistry