M. P. Landry

Deep Plasma Proteome Profiling by Modulating Single Nanoparticle Protein Corona with Small Molecules

This paper demonstrates that adding small molecules to plasma enhances nanoparticle protein corona diversity, significantly increasing the number of detectable proteins in plasma proteome profiling.

Predicting Serotonin Detection with DNA-Carbon Nanotube Sensors Across Multiple Spectral Wavelengths

The paper uses machine learning to predict serotonin detection by DNA-SWNT sensors across multiple wavelengths, showing DNA sequence's key role and limitations due to dataset size.

Covalent Attachment of Horseradish Peroxidase to Single-Walled Carbon Nanotubes for Hydrogen Peroxide Detection

This paper develops a platform for covalently attaching horseradish peroxidase to single-walled carbon nanotubes to create a hydrogen peroxide sensor with real-time imaging and selectivity.

Mapping the Morphology of DNA on Carbon Nanotube-Based Sensors in Solution using X-ray Scattering Interferometry

This study uses X-ray scattering interferometry to directly measure ssDNA geometries on SWCNTs in solution, revealing structural changes and sensing mechanisms.

Near Infrared Nanosensors Enable Optical Imaging of Oxytocin with Selectivity over Vasopressin in Acute Mouse Brain Slices

This study develops a near-infrared nanosensor to selectively image oxytocin in mouse brain slices, revealing release sites with a median size of 3 micrometers.

Fluorescence complementation enables quantitative imaging of cell penetrating peptide-mediated protein delivery in plants including WUSCHEL transcription factor

The paper introduces DCIP, a tool for quantitatively measuring protein delivery in plants, demonstrating its use with cell-penetrating peptides and showing delivery of a transcription factor.

Carbon nanotube biocompatibility in plants is determined by their surface chemistry

This study investigates the biocompatibility of single-walled carbon nanotubes in plants, finding that surface chemistry determines toxicity and cellular response.

Machine learning enables discovery of DNA-carbon nanotube sensors for serotonin

The paper uses machine learning to predict DNA sequences that create strong optical responses to serotonin in DNA-carbon nanotube sensors, discovering five new sensors with improved performance.

Polymer-Conjugated Carbon Nanotubes for Biomolecule Loading

This study optimizes DNA loading on polymer-conjugated carbon nanotubes, assesses stability, and evaluates toxicity in plant systems.

Supervised Learning Model Predicts Protein Adsorption to Carbon Nanotubes

The paper develops a random forest classifier to predict protein adsorption to carbon nanotubes using amino acid sequences, identifying key features associated with binding affinity.

Nanoparticle Cellular Internalization is Not Required for RNA Delivery to Mature Plant Leaves

This study shows that small spherical AuNPs can deliver siRNA efficiently to plant leaves without entering cells, challenging the need for nanoparticle internalization in RNA delivery.

Gold nanocluster mediated delivery of siRNA to intact plant cells for efficient gene knockdown

This paper develops a method using gold nanoclusters to deliver siRNA into plant cells, achieving efficient gene knockdown with minimal toxicity.

Transcriptomic and morphological response of SIM-A9 mouse microglia to carbon nanotube neuro-sensors

The paper examines the effects of SWCNT dopamine nanosensors on mouse microglia and introduces a passivation strategy to enhance biocompatibility and imaging performance.

Binding affinity and conformational preferences influence kinetic stability of short oligonucleotides on carbon nanotubes

This study investigates how binding affinity and conformational preferences affect the kinetic stability of short oligonucleotides on carbon nanotubes using simulations and experiments.

Surface Modification Effects on Single-Walled Carbon Nanotubes for Multimodal Optical Applications

This study shows that covalently functionalized single-walled carbon nanotubes retain fluorescence for molecular recognition, enabling their use in nanosensors and multiplexed applications.

Protein Corona Composition and Dynamics on Carbon Nanotubes in Blood Plasma and Cerebrospinal Fluid

The paper measures protein corona formation on carbon nanotubes and polystyrene nanoparticles in blood plasma and cerebrospinal fluid, identifying key proteins and interactions driving corona composition and dynamics.

Carbon Nanocarriers Deliver siRNA to Intact Plant Cells for Efficient Gene Knockdown

This study develops nanotube-based delivery of siRNA to plant cells, achieving efficient gene knockdown by overcoming cell wall barriers and nuclease degradation.

Corona exchange dynamics on carbon nanotubes by multiplexed fluorescence monitoring

This study measures real-time DNA and protein exchange dynamics on carbon nanotubes in solution, showing fibrinogen binds more strongly than albumin and affects dopamine sensor response.

CHEMOMETRIC APPROACHES FOR DEVELOPING INFRARED NANOSENSORS TO IMAGE ANTHRACYCLINES

This paper develops chemometric methods to screen nanosensors for imaging anthracyclines, identifying a doxorubicin-specific sensor with high sensitivity and selectivity.

High Aspect Ratio Nanomaterials Enable Delivery of Functional Genetic Material Without DNA Integration in Mature Plants

This study shows high aspect ratio nanomaterials can deliver functional genetic material to plants without DNA integration, using multiple species and demonstrating siRNA gene silencing.

Activity of Antimicrobial Peptides Decreases with Increased Cell Membrane Crossing Free Energy Cost

This study shows that increased intermolecular interactions in antimicrobial peptides raise the energy cost to cross bacterial membranes, reducing their antibacterial activity.