S. Jeong

Pre-challenge gut microbial signature predicts RhCMV/SIV vaccine efficacy in rhesus macaques

The paper identifies a gut microbial signature predictive of RhCMV/SIV vaccine efficacy in rhesus macaques using 16S rRNA analysis and compositional data techniques.

Predicting Serotonin Detection with DNA-Carbon Nanotube Sensors Across Multiple Spectral Wavelengths

The paper uses machine learning to predict serotonin detection by DNA-SWNT sensors across multiple wavelengths, showing DNA sequence's key role and limitations due to dataset size.

Serine synthesis pathway upregulated by E-cadherin is essential for the proliferation and metastasis of breast cancers

This study shows that E-cadherin upregulates the serine synthesis pathway in breast cancer cells, supporting proliferation and metastasis by providing metabolic precursors and resistance to oxidative stress.

Uniform cerebral organoid culture on a pillar plate by simple and reproducible spheroid transfer from an ultralow attachment well plate

This paper introduces a method to generate reproducible cerebral organoids from iPSCs using a pillar plate platform, improving throughput and reducing variability compared to traditional methods.

Near Infrared Nanosensors Enable Optical Imaging of Oxytocin with Selectivity over Vasopressin in Acute Mouse Brain Slices

This study develops a near-infrared nanosensor to selectively image oxytocin in mouse brain slices, revealing release sites with a median size of 3 micrometers.

Machine learning enables discovery of DNA-carbon nanotube sensors for serotonin

The paper uses machine learning to predict DNA sequences that create strong optical responses to serotonin in DNA-carbon nanotube sensors, discovering five new sensors with improved performance.

Positional isomers of a non-nucleoside substrate differentially affect myosin function

This study shows that positional isomers of a synthetic non-nucleoside triphosphate can differentially control myosin function by altering force and motion generation without changing myosin structure.

Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms

This study identifies the Btk SH2-kinase interface as critical for activation and shows that targeting it with a repebody inhibits B-cell neoplasms.

Graphene Quantum Dot Oxidation Governs Noncovalent Biopolymer Adsorption

This study investigates how oxidation levels of graphene quantum dots (GQDs) affect noncovalent adsorption of single-stranded DNA, showing strong adsorption on unoxidized GQDs and none on heavily oxidized ones.

CHEMOMETRIC APPROACHES FOR DEVELOPING INFRARED NANOSENSORS TO IMAGE ANTHRACYCLINES

This paper develops chemometric methods to screen nanosensors for imaging anthracyclines, identifying a doxorubicin-specific sensor with high sensitivity and selectivity.