Author

N. Pervolarakis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Immunology· 1

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Research Focus:cell type annotation· 4 Organism:human· 4 Assay:scRNA-seq· 4 Approach:statistical model· 4 Approach:deep learning· 3 Research Focus:differential expression· 3 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

K. Kessenbrock· 5 shared K. Nee· 3 shared Q. Nguyen· 3 shared D. Ma· 2 shared G. Hernandez· 2 shared H. Alshetaiwi· 2 shared Q. H. Nguyen· 2 shared Q. Nie· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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5 shared papersCancer Biology

K. Kessenbrock

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Author profile →

5 papers

Recent·Most cited

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

G. COULIS, D. Jaime, C. Guerrero-Juarez, J. Kastenschmidt, P. Farahat, Q. Nguyen, N. Pervolarakis, K. McLinden, L. Thurlow, S. Movahedi, B. Hughes, J. Duarte, A. Sorn, E. Montoya, I. Mozaffar, , A. Villalta

bioRxiv · Apr 18, 2023Immunology

Pre-neoplastic stromal cells drive BRCA1-mediated breast tumorigenesis

K. Nee, D. Ma, Q. H. Nguyen, N. Pervolarakis, J. Insua-Rodriguez, M. Pein, Y. Gong, G. Hernandez, H. Alshetaiwi, J. Williams, M. Rauf, K. R. Dave, K. Boyapati, C. Calderon, A. Markaryan, , K. Kessenbrock

The paper shows pre-neoplastic stromal cells promote BRCA1-driven breast cancer by inducing epithelial proliferation and altering differentiation.

bioRxiv · Oct 20, 2021 · PreprintCancer Biology

An In Vitro Vascularized Micro-Tumor Model of Human Colorectal Cancer Recapitulates In Vivo Drug Responses

S. J. Hachey, S. Movsesyan, Q. H. Nguyen, G. Burton-Sojo, A. Tankazyan, J. Wu, T. Hoang, M. M. Hatch, D. Zhao, E. Celaya, S. Gomez, G. T. Chen, R. T. Davis, K. Nee, N. Pervolarakis, , C. C. Hughes

This paper validates a vascularized micro-tumor model for colorectal cancer that better replicates in vivo drug responses than traditional 2D or 3D models.

bioRxiv · Mar 3, 2020Cancer Biology

Integrated single-cell transcriptomics and chromatin accessibility analysis reveals novel regulators of mammary epithelial cell identity

N. Pervolarakis, Q. Nguyen, G. Gutierrez, P. Sun, D. Jhutty, G. X. Zheng, C. M. Nemec, X. Dai, K. Watanabe, K. Kessenbrock

The paper integrates single-cell transcriptomics and chromatin accessibility analysis to identify novel regulatory elements in mouse mammary epithelial cells and their differentiation states.

bioRxiv · Aug 20, 2019Cell Biology

Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics

H. Alshetaiwi, N. Pervolarakis, L. L. McIntyre, D. Ma, Q. Nguyen, J. A. Rath, K. Nee, G. Hernandez, K. Evans, L. Torosian, A. Silva, C. Walsh, K. Kessenbrock

This study identifies unique molecular features of MDSCs using single-cell transcriptomics, revealing a distinct maturation trajectory and novel surface markers for their detection.

bioRxiv · Jul 15, 2019Cancer Biology