Author

Q. Nie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:statistical model· 5 Research Focus:cell-cell communication· 4 Assay:scRNA-seq· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2

Frequent Co-Authors

C. Guerrero-Juarez· 2 shared K. Kessenbrock· 2 shared N. Pervolarakis· 2 shared P. Zhou· 2 shared S. Othy· 2 shared A. MacLean· 1 shared A. Markaryan· 1 shared A. Moshensky· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

C. Guerrero-Juarez

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Calcyphosine is a microtubule-associated protein required for spindle formation and function

B. Setu, Q. Nie, G. Echele, S. A. Spencer

This study identifies CAPS as a microtubule-binding protein essential for spindle formation and mitosis, with potential implications for cancer biology.

bioRxiv · Dec 29, 2023 · PreprintCell Biology

Interruption of the Intratumor CD8:Treg Crosstalk Improves the Efficacy of PD-1 Immunotherapy

S. N. Geels, A. Moshensky, R. S. Sousa, B. L. Walker, R. Singh, G. Gutierrez, M. Hwang, T. R. Mempel, Q. Nie, S. Othy, F. Marangoni

This study shows that interrupting CD8:Treg crosstalk during PD-1 immunotherapy improves melanoma control by reducing Treg accumulation.

bioRxiv · May 15, 2023 · PreprintImmunology

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

G. COULIS, D. Jaime, C. Guerrero-Juarez, J. Kastenschmidt, P. Farahat, Q. Nguyen, N. Pervolarakis, K. McLinden, L. Thurlow, S. Movahedi, B. Hughes, J. Duarte, A. Sorn, E. Montoya, I. Mozaffar, , A. Villalta

bioRxiv · Apr 18, 2023Immunology

Pre-neoplastic stromal cells drive BRCA1-mediated breast tumorigenesis

K. Nee, D. Ma, Q. H. Nguyen, N. Pervolarakis, J. Insua-Rodriguez, M. Pein, Y. Gong, G. Hernandez, H. Alshetaiwi, J. Williams, M. Rauf, K. R. Dave, K. Boyapati, C. Calderon, A. Markaryan, , K. Kessenbrock

The paper shows pre-neoplastic stromal cells promote BRCA1-driven breast cancer by inducing epithelial proliferation and altering differentiation.

bioRxiv · Oct 20, 2021 · PreprintCancer Biology

Single-cell analysis of basal cell carcinoma reveals heat shock proteins promote tumor growth in response to WNT5A-mediated inflammatory signals

C. Guerrero-Juarez, G. Lee, Y. Liu, S. Wang, Y. Sha, R. Chow, T. Nguyen, S. Aasi, M. Karikomi, M. Drummond, Q. Nie, K. Sarin, S. X. Atwood

This study uses single-cell RNA sequencing to show heat shock proteins promote BCC growth in response to WNT5A-mediated inflammatory signals from the tumor microenvironment.

bioRxiv · Oct 7, 2021 · PreprintCancer Biology

Divergent resistance mechanisms to immunotherapy explains response in different skin cancers.

E. Dollinger, D. Bergman, P. Zhou, S. Atwood, Q. Nie

This study identifies divergent immune resistance mechanisms in melanoma and basal cell carcinoma that explain differential responses to checkpoint immunotherapy.

bioRxiv · Sep 15, 2020Cancer Biology

Rapidly cycling stem cells regenerate the intestine independent of Lgr5high cells

X. Sheng, Z. Lin, C. Lv, C. Shao, X. Bi, M. Deng, J. Xu, C. F. Guerrero-Juarez, M. Li, X. Wu, R. Zhao, X. Liu, Q. Wang, Q. Nie, W. Cui, , Z. Yu

This study identifies Msi1+ cells as rapidly cycling intestinal stem cells that regenerate the intestine independently of Lgr5high cells.

bioRxiv · Oct 21, 2019 · PreprintCell Biology