Author

N. Pham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

M. Auer· 2 shared A. Balwierz· 1 shared A. Fumagalli· 1 shared A. G. Cheng· 1 shared A. H. Ling· 1 shared A. Ishiyama· 1 shared A. van Oudenaarden· 1 shared C. Evelo· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBiochemistry

M. Auer

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Author profile →

5 papers

Recent·Most cited

An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying translocation RCC.

M. Ganpat, F. Morales-Rodriguez, N. Pham, P. Lijnzaad, T. de Souza, S. Derakhshan, A. Fumagalli, P. Zeller, A. Balwierz, D. Ayyildiz, M. M. van den Heuvel-Eibrink, R. R. de Krijger, A. van Oudenaarden, T. Margaritis, S. M. Chuva de Sousa Lopes, J. Drost

This study creates an engineered tumor organoid model of tRCC using SFPQ-TFE3 fusion expression, revealing epithelium-to-mesenchymal differentiation and Wnt signaling involvement in tumor transformation.

bioRxiv · Sep 1, 2023 · PreprintCancer Biology

Different B cell activation patterns in asymptomatic and symptomatic COVID-19 patients

N. Pham, N. Talih, F. Ehrhart, C. Evelo, M. Kutmon

This study identifies distinct B cell activation patterns in asymptomatic and symptomatic COVID-19 patients using a transcriptomics dataset and pathway analysis.

bioRxiv · Dec 19, 2022 · PreprintImmunology

Single-cell transcriptomic atlas reveals increased regeneration in diseased human inner ears

T. Wang, A. H. Ling, S. E. Billings, D. K. Hosseini, Y. Vaisbuch, G. S. Kim, P. J. Atkinson, Z. N. Sayyid, K. A. Aaron, D. Wagh, N. Pham, M. Scheibinger, A. Ishiyama, P. Santa Maria, N. H. Blevins, , A. G. Cheng

The paper presents a single-cell transcriptomic atlas of human inner ears, revealing increased regeneration in diseased utricles and new cell type markers.

bioRxiv · Oct 29, 2022 · PreprintCell Biology

Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay

J. Koszela, N. Pham, D. Evans, S. Mann, I. Perez-Pi, S. Shave, D. Ceccarelli, F. Sicheri, M. Tyers, M. Auer

This paper introduces a fluorescent confocal on-bead assay to real-time track ubiquitination cascades and identifies new inhibitor activities against Ube1.

bioRxiv · Feb 21, 2018Biochemistry

Detecting Drug-Target Binding In Cells Using Fluorescence Activated Cell Sorting Coupled With Mass Spectrometry Analysis

K. Wilson, S. P. Webster, J. P. Iredale, X. Zheng, N. Z. M. Homer, N. Pham, M. Auer, D. J. Mole

This paper introduces a new method called TAPS to assess drug-target binding in cells, demonstrating its effectiveness with the challenging KMO target.

bioRxiv · Apr 3, 2017Pharmacology & Toxicology