Author

N. Ranson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Basle· 2 shared B. van den Berg· 2 shared J. White· 2 shared A. C. Kalli· 1 shared A. Cartmell· 1 shared A. Glenwright· 1 shared A. Kohl· 1 shared A. Macdonald· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

A. Basle

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mechanism of human PINK1 activation at the TOM complex in a reconstituted system

O. Raimi, H. Ojha, K. Ehses, V. Dederer, S. Lange, C. P. Rivera, T. Deegan, Y. Chen, M. Wightman, R. Toth, K. Labib, S. Mathea, N. Ranson, R. Fernandez-Busnadiego, M. Muqit

This study identifies TOM20, TOM70, TOM40, and associated subunits as critical for PINK1 activation in a reconstituted yeast system, providing insights for PINK1 activator development.

bioRxiv · Dec 23, 2023Biochemistry

Inhibitors of the Small Membrane (M) Protein Viroporin Prevent Zika Virus Infection

E. Brown, G. Swinscoe, D. Lefteri, R. Singh, A. Moran, R. Thompson, D. Maskell, H. Beaumont, M. J. Bentham, C. Donald, A. Kohl, A. Macdonald, N. Ranson, R. Foster, C. S. McKimmie, , S. C. Griffin

This study identifies the ZIKV M protein as a therapeutic target, showing that inhibitors like rimantadine block viral infection in vitro and in vivo by targeting M-formed channels.

bioRxiv · Mar 11, 2021Microbiology

Insights into glycan import by a prominent gut symbiont

D. Gray, J. White, A. Oluwole, P. Rath, A. Glenwright, A. Mazur, M. Zahn, A. Basle, C. Morland, S. Evans, A. Cartmell, C. V. Robinson, S. Hiller, N. Ranson, D. Bolam, B. van den Berg

This study characterizes the SusCD protein complex in Bacteroides thetaiotaomicron to elucidate its role in glycan uptake, revealing structural and functional insights into ligand binding and transport dynamics.

Nature Communications · Jan 4, 2021Peer-reviewedMicrobiology

Dynamic oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis

M. Madej, J. White, Z. Nowakowska, S. Rawson, C. Scavenius, J. Enghild, G. Bereta, K. Pothula, U. Kleinekathoefer, A. Basle, N. Ranson, J. Potempa, B. van den Berg

This study identifies RagAB as the oligopeptide transporter in P. gingivalis, revealing its structure and mechanism for nutrient uptake from the extracellular environment.

bioRxiv · Sep 4, 2019Microbiology