N. Shukla

Mutant Prion Protein Endoggresomes are Hubs for Local Axonal Organelle-Cytoskeletal Remodeling

This study identifies mutant PrP endoggresomes as hubs causing cytoskeletal and transport deficits in axons, leading to organelle retention and mitochondrial dysfunction in prionopathies.

Novel CAF-identifiers via transcriptomic analysis in oral cancer patients

The paper identifies novel CAF markers in oral cancer through transcriptomic analysis to distinguish CAFs from other cell types.

A complex role of Arabidopsis CDKD;3 in meiotic progression and cytokinesis

This study identifies CDKD;3 as a gene that suppresses meiotic defects in smg7 mutants by promoting meiotic exit and enabling cytokinesis in Arabidopsis.

Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains

This study identifies ACE2 receptor usage by SARS-like coronaviruses, showing clade 3 viruses use Rhinolophus ACE2 while clade 2 viruses may use an unknown receptor.

PxdA interacts with the DipA phosphatase to regulate endosomal hitchhiking of peroxisomes

The paper identifies PxdA as a specific molecular linker for peroxisome hitchhiking on early endosomes in A. nidulans and reveals DipA as a regulator of this process.

Temporal gating of SIRT1 functions by O-GlcNAcylation prevents hyperglycemia and enables physiological transitions in liver

This study identifies nutrient-dependent O-GlcNAcylation of SIRT1 as a mechanism controlling hepatic metabolism and insulin signaling during fasted-to-refed transitions.