PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade
N. Srour, O. D. Villareal, Z. Yu, S. Preston, W. H. Miller, M. Szewczyk, D. Barsyte-Lovejoy, H. Xu, S. V. del Rincon, S. Richard
This study shows PRMT7 inhibition enhances anti-tumor immunity and improves response to immune checkpoint blockade in melanoma by modulating immune cell infiltration and PD-L1 expression.
bioRxiv · Jul 28, 2021Immunology