Author

S. V. del Rincon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2

Frequent Co-Authors

W. H. Miller· 4 shared C. Goncalves· 3 shared F. Huang· 3 shared J. Su· 2 shared M. Basik· 2 shared N. Gagnon· 2 shared S. Preston· 2 shared A. Aguilar-Mahecha· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersCancer Biology

W. H. Miller

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Tunable PhenoCycler Imaging of the Murine Pre-Clinical Tumour Microenvironments

M. J. Abraham, C. Goncalves, P. McCallum, V. Gupta, S. E. J. Preston, F. Huang, H. Chou, N. Gagnon, N. A. Johnson, W. H. Miller, K. K. Mann, S. V. del Rincon

This study uses PhenoCycler imaging to analyze the tumor microenvironment in murine cancer models, revealing distinct TME features and cell-cell contact differences across cancer types.

bioRxiv · Sep 18, 2023Cancer Biology

Clinical proteomics reveals vulnerabilities in non-invasive breast ductal carcinoma and drives personalized treatment strategies.

G. Mitsa, L. Florianova, J. Lafleur, A. Aguilar-Mahecha, R. P. Zahedi, S. V. Del Rincon, M. Basik, C. H. Borchers, G. Batist

The paper uses clinical proteomics to identify biomarkers and metabolic vulnerabilities in DCIS, informing therapeutic strategies and developing a targeted proteomics assay for cancer-related pathways.

bioRxiv · Jul 11, 2023 · PreprintCancer Biology

Disrupting peroxisomes alters lipid metabolism in melanoma and uncovers a novel therapeutic vulnerability in combination with MAPK-targeted therapies

F. Huang, F. Cai, M. S. Dahabieh, K. Gunawardena, A. Talebi, J. Dehairs, F. El-Turk, J. Y. Park, C. Goncalves, N. Gagnon, J. Su, P. Gaub, J.-S. Joyal, J. J. Mitchell, J. V. Swinnen, , S. V. del Rincon

This paper identifies a metabolic vulnerability in melanoma cells by disrupting peroxisomes and shows that combining this with MAPK-targeted therapies enhances anti-tumor effects.

bioRxiv · Oct 25, 2022 · PreprintCancer Biology

PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade

N. Srour, O. D. Villareal, Z. Yu, S. Preston, W. H. Miller, M. Szewczyk, D. Barsyte-Lovejoy, H. Xu, S. V. del Rincon, S. Richard

This study shows PRMT7 inhibition enhances anti-tumor immunity and improves response to immune checkpoint blockade in melanoma by modulating immune cell infiltration and PD-L1 expression.

bioRxiv · Jul 28, 2021Immunology

The pleiotropic effects of the MNK1/2-eIF4E axis support immune suppression and metastasis in a model of postpartum breast cancer.

Q. Guo, M. Bartish, C. Goncalves, F. Huang, S. S. Krisna, S. Preston, A. Emond, V. Z. Li, C. Duerr, Y. Gui, A. Cleret-Buhot, P. Thebault, H. Lefrere, L. Lenaerts, D. Plourde, , W. H. Miller

This study shows that the MNK1/2-eIF4E axis promotes immune suppression and metastasis in postpartum breast cancer by affecting both tumor and non-tumor cells.

bioRxiv · Sep 7, 2020 · PreprintCancer Biology