Author

J.-M. Lambert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Marchalot· 2 shared L. Delpy· 2 shared A. Bonaud· 1 shared C. Carrion· 1 shared C. Sirac· 1 shared F. Boyer· 1 shared F. Lechouane· 1 shared J. Cook-Moreau· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

A. Marchalot

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Splice switching oligonucleotide mediated gene knockdown in B cells and plasma cells

L. Delpy, A. Marchalot, J.-M. Lambert, F. Boyer, J. Pollet, J. Cook-Moreau, J. Feuillard, N. Faumont

This paper demonstrates the effectiveness of splice switching oligonucleotides in knocking down c-REL and RELA expression in B cells and plasma cells, with potential therapeutic applications in B-lineage cancers.

bioRxiv · Sep 18, 2020 · PreprintImmunology

New models to study plasma cells in mouse based on the restriction of IgJ expression to antibody secreting cells.

M. V. Ayala, A. Bonaud, S. Bender, J.-M. Lambert, F. Lechouane, C. Carrion, M. Cogne, V. Pascal, C. Sirac

The paper introduces two new mouse models, IgJGFP and IgJCreERT2, for studying plasma cells by leveraging IgJ expression as a marker for antibody-secreting cells.

bioRxiv · Aug 13, 2020 · PreprintImmunology

Uncoupling splicing from transcription using antisense oligonucleotides reveals a dual role for I exon donor splice sites in antibody class switching

A. Marchalot, M. O. Ashi, J.-M. Lambert, N. Srour, L. Delpy, S. Le Pennec

This study uses antisense oligonucleotides to show that I exon donor splice sites are essential for both transcriptional regulation and splicing during antibody class switching.

bioRxiv · Nov 22, 2019Immunology