A20 is an immune tolerance factor that can determine islet transplantoutcomes.
N. W. Zammit, S. N. Walters, K. Seeberger, G. S. Korbutt, S. T. Grey
This study shows that increasing A20 expression in islet grafts improves allogeneic survival and reduces immune rejection, supporting the use of alternative islet sources with reduced immunosuppression.
bioRxiv · Sep 16, 2019Immunology