Author

Neil C. Sheppard

Every paper listing this name carries an ORCID.

Identified by ORCID

Neil C. SheppardiD2 papers · Abramson Cancer Center

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Carl H. JuneiD· 2 shared Ajay S. ThatteiD· 1 shared Alex G. HamiltoniD· 1 shared Alexander A Shestov· 1 shared Alvin J. Mukalel· 1 shared Bakir Valentic· 1 shared C. Pritchett FrazeeiD· 1 shared Christian G. Figueroa‐EspadaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

Carl H. JuneORCID

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Author profile →

2 papers

Recent·Most cited

Receptor-guided engineering of oncolytic vaccinia creates a synthetic support niche for off-the-shelf NK cell therapy

Reza Rezaei, Zhiyang Gan, Ngomu Akeem Akilimali, Jordan Reff, Meiyin Lin, Yansen Xiao, Kush Parikh, Darsh Vithlani, Bakir Valentic, Alexander A Shestov, Ugur Uslu, Taha Azad, Roddy S OConnor, Carl H. June, Neil C. Sheppard

This paper develops a framework to engineer oncolytic vaccinia virus to support off-the-shelf NK cells by aligning viral payloads with NK cell manufacturing limitations.

bioRxiv · Nov 9, 2026 · PreprintBioengineering

Bioinspired Oxidized mRNA Lipid Nanoparticles for Ex Vivo Engineering of Chimeric Antigen Receptor Macrophages Targeting Solid Tumors

Alvin J. Mukalel, Tina Tylek, Hannah C. Geisler, Erin M. O’Brien, C. Pritchett Frazee, Jacqueline J. Li, Ajay S. Thatte, Hannah C. Safford, Christian G. Figueroa‐Espada, Mohamad‐Gabriel Alameh, Alex G. Hamilton, David Mai, Neil C. Sheppard, Carl H. June, Drew Weissman, , Michael J. Mitchell

This paper develops a bioinspired oxidized lipid nanoparticle platform for mRNA-based engineering of CAR-Ms to target solid tumors, showing improved delivery and tumor-killing efficacy.

Bioengineering & Translational Medicine · Mar 30, 2026Peer-reviewedBioengineering