Author

Nejia Lassoued

Université du Québec à Montréal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Nicolas PiloniD· 3 shared Alassane Gary· 2 shared Rodolphe Soret· 2 shared Alexis YeroiD· 1 shared Ann AspirotiD· 1 shared Christoph A. ThaissiD· 1 shared Christophe C. FaureiD· 1 shared Daniela Min Jing Che Jin· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersDevelopmental Biology

Nicolas PilonORCID

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3 papers

Recent·Most cited

GDNF enemas improve epithelial and immune defects in both aganglionic and ganglionic colon of Hirschsprung mice

Nejia Lassoued, Jacob Trudel, Marie A Lefèvre, Alassane Gary, Zhiqiang Guo, Alexis Yero, Mohammad-Ali Jenabian, Rodolphe Soret, Nicolas Pilon

This study shows that GDNF enemas improve epithelial and immune defects in both aganglionic and ganglionic colon of Hirschsprung mice, reducing bacterial translocation and inflammation.

bioRxiv · Sep 1, 2026 · PreprintDevelopmental Biology

GDNF regenerates the missing enteric nervous system of Hirschsprung mice via non-canonical signaling in diverse subtypes of tissue-resident progenitors

Alassane Gary, Rodolphe Soret, Marie A. Lefevre, Nejia Lassoued, Ann Aspirot, Christophe C. Faure, Nicolas Pilon

This study shows GDNF regenerates the missing enteric nervous system in Hirschsprung mice through non-canonical signaling in tissue-resident progenitors, suggesting potential for broader therapeutic applications.

bioRxiv · May 23, 2025 · PreprintNeuroscience

Dietary manipulation of intestinal microbes prolongs survival in a mouse model of Hirschsprung disease

Naomi E. Butler Tjaden, Megan J. Liou, Sophie E. Sax, Nejia Lassoued, Meng Lou, Sabine Schneider, Katherine Beigel, Joshua D. Eisenberg, Emma Loeffler, Sierra E. Anderson, Guang Yan, Lev Litichevskiy, Lenka Dohnalová, Yixuan Zhu, Daniela Min Jing Che Jin, , Robert O. Heuckeroth

This study shows that diet can significantly affect survival in a mouse model of Hirschsprung disease by altering gut microbes, metabolites, and epithelial gene expression.

bioRxiv · Feb 10, 2025 · PreprintCell Biology