Author

Nicholas Coungeris

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:organoid / primary culture· 1 Research Focus:synaptic & neural circuits· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Andrew S. LaCroixiD· 2 shared Corey M. RountreeiD· 2 shared Victoria Alstat· 2 shared Christopher M. Butt· 1 shared Eva Schmidt· 1 shared J. Lowry Curley· 1 shared Megan Morris· 1 shared Michael John MooreiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

Andrew S. LaCroixORCID

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2 papers

Recent·Most cited

Human CNS-3D organoids predict clinical seizure liability from calcium network activity

Andrew S. LaCroix, Nicholas Coungeris, Victoria Alstat, Corey M. Rountree, Paolo Botta, Muhammad Maaz, Christopher M. Butt

The paper uses human CNS-3D organoids to predict clinical seizure liability based on calcium network activity, achieving high sensitivity and specificity.

bioRxiv · May 23, 2026 · PreprintPharmacology & Toxicology

Long-Term Potentiation and Closed-Loop Learning in Paired Brain Organoids for CNS Drug Discovery

Corey M. Rountree, Eva Schmidt, Nicholas Coungeris, Victoria Alstat, Andrew S. LaCroix, Megan Morris, Michael John Moore, J. Lowry Curley

This study demonstrates LTP and closed-loop learning in paired brain organoids, showing BDNF's role in enhancing plasticity and linking game performance to cognitive function for CNS drug discovery.

bioRxiv · Jul 3, 2025 · PreprintBioengineering