Paolo Botta

The paper uses in vivo imaging to show PACAP38 preferentially dilates dural vessels and identifies this as a measurable therapeutic target for migraine treatments.

The paper uses human CNS-3D organoids to predict clinical seizure liability based on calcium network activity, achieving high sensitivity and specificity.

This study shows that visual evoked potentials change in early tauopathy, suggesting they could be a biomarker for early disease stages.

The paper investigates early neuronal activity impairments in the rTg4510 tauopathy mouse model, finding reduced responsivity and altered oscillatory patterns in visual cortex neurons.

The paper identifies an amygdala circuit that mediates experience-dependent momentary exploratory arrests in mice without affecting place preference or anxiety-like behaviors.