Author

Nikhita Pasnuri

Memorial Sloan Kettering Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1

Frequent Co-Authors

Dana Pe’eriD· 3 shared Tal NawyiD· 3 shared Andrew R Moorman· 2 shared Ahmed M. ElhossinyiD· 1 shared Ananya Nandula· 1 shared Andrea C. ChaikovskyiD· 1 shared Anna MathioudakiiD· 1 shared Anupriya SinghaliD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

Dana Pe’erORCID

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Author profile →

4 papers

Recent·Most cited

The basal cell state maintains pancreatic cancers by controlling an immunosuppressive circuit

Anupriya Singhal, Kate Ryan, Samuel Rose, Hannah C. Styers, Jung Kim, Nikhita Pasnuri, Ashlyn Moore, Jose Llamosas, Emily Chen, Josephine Adams, Ananya Nandula, Roshan Sharma, Zhuxuan Li, Tal Nawy, Yan Yan, , Tuomas Tammela

This study identifies the basal cell state in pancreatic cancer as critical for maintaining tumors through an immunosuppressive circuit, showing its ablation leads to tumor collapse.

bioRxiv · Jul 14, 2026 · PreprintCancer Biology

Oncogenic and tumor-suppressive forces converge on a progenitor niche at the benign-to-malignant transition

Jose Reyes, Isabella S. Del Priore, Andrea C. Chaikovsky, Nikhita Pasnuri, Ahmed M. Elhossiny, Jin Park, Philipp Weiler, Tobias Krause, Andrew R Moorman, Catherine Snopkowski, Meril T. Takizawa, Cassandra Burdziak, Nalin Ratnayeke, Ignas Masilionis, Yu-Jui Ho, , Scott W. Lowe

In mouse pancreatic cancer models, p53, CDKN2A and SMAD4 programs converge on a rare Kras-mutant progenitor-like state whose niche KRAS inhibition collapses and p53 loss expands.

Cell · Apr 15, 2026Peer-reviewedCancer Biology✦ In-depth digest

Segger: Fast and accurate cell segmentation of imaging-based spatial transcriptomics data

Elyas Heidari, Andrew R Moorman, Dániel Unyi, Nikhita Pasnuri, Gleb D. Rukhovich, Domenico Calafato, Anna Mathioudaki, Joseph Minhow Chan, Tal Nawy, Moritz Gerstung, Dana Pe’er, Oliver Stegle

Segger improves cell segmentation in spatial transcriptomics by using a graph neural network, achieving high sensitivity and speed with minimal manual intervention.

bioRxiv · Mar 14, 2025 · PreprintBioinformatics

Buffered EGFR signaling regulated by spitz to argos expression ratio is critical for patterning the Drosophila eye

Nikhita Pasnuri, Manish Jaiswal, Krishanu Ray, Aprotim Mazumder

The paper shows that the ratio of spitz to argos expression, not absolute levels, determines Drosophila eye patterning through buffered EGFR signaling.

PLoS Genetics · Feb 2, 2023Peer-reviewedDevelopmental Biology