Author

Nobuko Uchida

Stanford Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Renata M. MartiniD· 2 shared Anders Laustsen· 1 shared Anna E. EastmaniD· 1 shared Benjamin F Ohene-Gambill· 1 shared Chang N. KimiD· 1 shared Claudia Katharina PetritschiD· 1 shared Daniel Dan LiuiD· 1 shared Daniel P. DeveriD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Renata M. MartinORCID

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Author profile →

3 papers

Recent·Most cited

Isolation of postnatal human neural stem cells

Daniel Dan Liu, Anna E. Eastman, Nicole L. Womack-Gambrel, Chang N. Kim, Joy Q. He, Suyash Raj, Emily E. Reilly, Rahul Sinha, Nobuko Uchida, Kelly Chau, Benjamin F Ohene-Gambill, Samrat Thapa, Emon Nasajpour, Julia A. Belk, Norma F Neff, , Irving L. Weissman

The paper isolates and characterizes two postnatal human neural stem cell subsets, showing their fate biases and decline in frequency over time.

bioRxiv · Jun 12, 2026 · PreprintNeuroscience

Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington's disease phenotypes in R6/2 mice

Danielle A. Simmons, Sridhar Selvaraj, Tingshuo Chen, Gloria Cao, Talita Sauto Camelo, Tyne L.M. McHugh, Selena Gonzalez, Renata M. Martin, Juste Simanauskaite, Nobuko Uchida, Matthew Hebden Porteus, Frank M. Longo

This study shows that human striatal progenitor cells overexpressing BDNF and with inducible safety switches improve HD symptoms in R6/2 mice.

Molecular Therapy — Methods & Clinical Development · Jan 22, 2025Peer-reviewedNeuroscience

Selection-free, high frequency genome editing by homologous recombination of human pluripotent stem cells using Cas9 RNP and AAV6

Renata M. Martin, Kazuya Ikeda, Nobuko Uchida, Kyle Cromer, Toshi Nishimura, Daniel P. Dever, Joab Camarena, Rasmus Bak, Anders Laustsen, Martin R. Jakobsen, Volker Wiebking, Vittorio Sebastiano, Hiromitsu Nakauchi, Matthew Porteus

This paper introduces a Cas9/AAV6 system for high-frequency genome editing in human pluripotent stem cells without selection markers, achieving up to 94% integration efficiency for large DNA cassettes.

bioRxiv · Jan 23, 2018 · PreprintBioengineering