Author

Nontokozo V. Mdluli

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Ellie N Hulit· 2 shared Jeffrey R. MaslankaiD· 2 shared Joshua E. DennyiD· 2 shared Michael C. AbtiD· 2 shared Mohamad‐Gabriel AlamehiD· 2 shared Daivon D Brown· 1 shared Dana Borden LacyiD· 1 shared F. Christopher Peritore‐GalveiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

Ellie N Hulit

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2 papers

Recent·Most cited

Immunotherapy restores therapeutic efficacy of fecal microbiome transplants to treat Clostridioides difficile

Subham Mridha, Md Zahidul Alam, Joshua E. Denny, Ellie N Hulit, Jeffrey R. Maslanka, Nontokozo V. Mdluli, Minh Tran-Ha, Kevin S Mears, Daivon D Brown, Mohamad‐Gabriel Alameh, Michael C. Abt

This study shows that IL-10 signaling deficiency impairs FMT engraftment and C. difficile resolution, and that IL-10 immunotherapy can restore FMT efficacy in mice.

bioRxiv · Sep 23, 2026 · PreprintImmunology

Clostridioides difficile toxin A and toxin B inhibit toxin-specific adaptive immune responses through glucosyltransferase-dependent activity

Jeffrey R. Maslanka, Jennifer Londregan, Joshua E. Denny, Ellie N Hulit, Nontokozo V. Mdluli, F. Christopher Peritore‐Galve, Md. Zahidul Alam, Mohamad‐Gabriel Alameh, Dana Borden Lacy, Joseph P. Zackular, Michael C. Abt

This study shows that C. difficile toxins A and B inhibit their own antigen-specific immune responses via glucosyltransferase activity, contributing to recurrent infections.

Mucosal Immunology · Aug 18, 2025Peer-reviewedImmunology