Author

S. Prisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1

Frequent Co-Authors

F. Kazmirczak· 3 shared J. B. Mendelson· 3 shared K. Prins· 3 shared L. M. Hartweck· 2 shared N. T. Vogel· 2 shared A. DE REYNIES· 1 shared A. Der Vartanian· 1 shared B. Kremer· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBiochemistry

F. Kazmirczak

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Junctophilin-2 Regulates Mitochondrial Metabolism

S. Prisco, L. M. Hartweck, F. Kazmirczak, J. B. Mendelson, S. L. Deng, S. K. Lahiri, X. Wehrens, K. Prins

This study shows JPH2 regulates mitochondrial metabolism in the right ventricle, with gene therapy improving RV function in a rat model of RVD.

bioRxiv · Feb 7, 2023Physiology

Ferroptosis Integrates Mitochondrial Derangements and Pathological Inflammation to Promote Pulmonary Hypertension

F. Kazmirczak, N. T. Vogel, S. Prisco, M. T. Patterson, J. Annis, R. T. Moon, L. M. Hartweck, J. B. Mendelson, M. Kim, N. Laixto Mancripe, T. Markowski, L. Higgins, C. Guerrero, B. Kremer, M. Blake, , K. Prins

This study investigates how ferroptosis contributes to pulmonary hypertension by integrating mitochondrial dysfunction and inflammation, showing that inhibiting ferroptosis reduces disease severity.

bioRxiv · Jan 19, 2023 · PreprintBiochemistry

Intermittent Fasting Activates AMP-Kinase to Restructure Right Ventricular Lipid Metabolism and Microtubules in Two Rodent Models of Pulmonary Arterial Hypertension

F. Kazmirczak, L. Hartweck, N. T. Vogel, J. B. Mendelson, J. Park, R. M. Raveendran, J. O-Uchi, B. S. Jhun, S. Prisco, K. Prins

This study shows intermittent fasting activates AMPK in rodent PAH models, improving RV lipid metabolism, mitochondrial function, and microtubule structure.

bioRxiv · Mar 7, 2022Biochemistry

The PAXFOXO1s trigger fast trans-differentiation of chick embryonic neural cells into alveolar rhabdomyosarcoma with tissue invasive properties limited by S phase entry inhibition

G. GONZALEZ CURTO, A. Der Vartanian, Y. FRARMA, L. Manceau, L. Baldi, S. Prisco, N. ELAROUCI, F. Causeret, M. RIGOLET, F. AURADE, A. DE REYNIES, V. CONTREMOULINS, F. RELAIX, O. FAKLARIS, J. BRISCOE, , V. RIBES

This study shows PAXFOXO1 fusion proteins drive neural cells to become ARMS-like cells but are limited by G1 cell cycle arrest, which can be overcome by CYCLIN D1 or MYCN.

bioRxiv · May 18, 2020 · PreprintCancer Biology