Author

O. Gozani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. G. Casanova· 1 shared A. M. Benitez· 1 shared A. Palencia· 1 shared C. E. Peters· 1 shared E. Bourova-Flin· 1 shared E. H. Pulido· 1 shared F. Ielasi· 1 shared G. M. Jang· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. G. Casanova

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis

A. G. Casanova, G. S. Roth, S. Hausmann, X. Lu, L. Belmudes, E. Bourova-Flin, N. M. Flores, A. M. Benitez, M. Caporicci, J. Vayr, S. Blanchet, F. Ielasi, S. Rousseaux, P. Hainaut, O. Gozani, , N. Reynoird

This study identifies SMYD2 as a master regulator of breast cancer metastasis and shows that targeting the SMYD2-BCAR3-FMNL axis can prevent metastatic spread.

bioRxiv · Sep 18, 2023Cancer Biology

Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3

C. E. Peters, U. Schulze-Gahmen, M. Eckhardt, G. M. Jang, J. Xu, E. H. Pulido, M. Ott, O. Gozani, K. A. Verba, R. Hüttenhain, J. Carette, N. J. Krogan

The paper reports the cryo-EM structure of SETD3 interacting with enterovirus protease 2A and shows that mutations in the SET domain reduce binding and protect against infection.

bioRxiv · Jun 22, 2022Biophysics