Author

O. M. Habeeb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4

Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

C. H. Contag· 4 shared C. V. Maduka· 4 shared M. M. Kuhnert· 4 shared S. B. Goodman· 3 shared A. Tundo· 2 shared A. V. Makela· 2 shared E. Ural· 2 shared M. Alhaj· 2 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersBioengineering

C. H. Contag

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Immunometabolic cues recompose and reprogram the microenvironment around biomaterials

C. V. Maduka, A. D. Schmitter-Sanchez, A. V. Makela, E. Ural, K. B. Stivers, H. Pope, M. M. Kuhnert, O. M. Habeeb, A. Tundo, M. Alhaj, A. Kiselev, S. Chen, A. J. Olive, K. D. D. Hankenson, R. Narayan, , C. H. Contag

The paper shows that immunometabolic cues around biomaterials influence immune cell trafficking and microenvironment composition, promoting a pro-regenerative state through metabolic reprogramming.

bioRxiv · Jul 30, 2023Bioengineering

Stereochemistry Determines Immune Cellular Responses to Polylactide Implants

C. V. Maduka, M. Alhaj, E. Ural, M. M. Kuhnert, O. M. Habeeb, A. L. Schilmiller, K. D. Hankenson, S. B. Goodman, R. Narayan, C. H. Contag

This study shows that PLA stereochemistry affects immune responses through differential metabolic changes in macrophages and fibroblasts, with stereocomplex PLA increasing proinflammatory cytokines via glycolysis.

bioRxiv · Oct 27, 2022Bioengineering

Elevated oxidative phosphorylation is critical for immune cell activation by polyethylene wear particles

C. V. Maduka, M. M. Kuhnert, O. M. Habeeb, A. Tundo, A. V. Makela, S. B. Goodman, C. H. Contag

The paper shows that elevated oxidative phosphorylation in macrophages exposed to polyethylene particles increases ROS and proinflammatory cytokines, suggesting a role in inflammation and implant failure.

bioRxiv · Oct 19, 2022Bioengineering

Glycolytic reprogramming underlies immune cell activation by polyethylene wear particles

C. V. Maduka, O. M. Habeeb, M. M. Kuhnert, M. Hakun, S. B. Goodman, C. H. Contag

The paper shows that polyethylene particles alter immune cell metabolism, leading to glycolytic reprogramming and inflammation, which can be inhibited to promote bone integration.

bioRxiv · Oct 14, 2022Bioengineering