Author

A. L. Schilmiller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Evolutionary Biology· 1 Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metagenomics· 2 Organism:plant (other)· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. D. Jones· 1 shared B. J. Leong· 1 shared C. H. Contag· 1 shared C. V. Maduka· 1 shared D. Chen· 1 shared D. Lybrand· 1 shared E. Ural· 1 shared H. Hong· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBiophysics

A. D. Jones

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Author profile →

5 papers

Recent·Most cited

Stereochemistry Determines Immune Cellular Responses to Polylactide Implants

C. V. Maduka, M. Alhaj, E. Ural, M. M. Kuhnert, O. M. Habeeb, A. L. Schilmiller, K. D. Hankenson, S. B. Goodman, R. Narayan, C. H. Contag

This study shows that PLA stereochemistry affects immune responses through differential metabolic changes in macrophages and fibroblasts, with stereocomplex PLA increasing proinflammatory cytokines via glycolysis.

bioRxiv · Oct 27, 2022Bioengineering

Lipid Bilayer Induces Contraction of the Denatured State Ensemble of a Helical-Bundle Membrane Protein

K. Gaffney, R. Guo, M. D. Bridges, D. Chen, S. Muhammednazaar, M. Kim, Z. yang, A. L. Schilmiller, N. F. Faruk, X. Peng, A. D. Jones, L. Sun, W. L. Hubbell, T. Sosnick, H. Hong

This study investigates the conformation and dynamics of the denatured state ensemble (DSE) of a membrane protein in a native lipid bilayer, finding it is dynamic and partially expanded.

bioRxiv · May 17, 2021Biophysics

Dioxin-elicited decrease in cobalamin redirects hepatic propionyl-CoA metabolism to the β-oxidation-like pathway resulting in acrylyl-CoA conjugate accumulation

K. Orlowska, R. R. Fling, R. Nault, W. J. Sink, A. L. Schilmiller, T. Zacharewski

This study shows TCDD decreases cobalamin, inhibits MUT activity, and redirects propionyl-CoA metabolism to a Cbl-independent β-oxidation-like pathway, leading to acrylyl-CoA accumulation and hepatotoxicity.

bioRxiv · Mar 24, 2021Pharmacology & Toxicology

A domestic plant differs from its wild relative along multiple axes of within-plant trait variability and diversity

M. L. Robinson, A. L. Schilmiller, W. C. Wetzel

This study finds that domestication and crop improvement in alfalfa increased within-plant trait variability for multiple traits, including chemical diversity and trichomes, while reducing variability in phytochemical composition.

bioRxiv · Nov 14, 2020Evolutionary Biology

Evolution of metabolic novelty: a trichome-expressed invertase creates specialized metabolic diversity in wild tomato

B. J. Leong, D. Lybrand, Y.-R. Lou, P. Fan, A. L. Schilmiller, R. L. Last

The paper identifies a trichome-expressed invertase in wild tomato that converts acylsucroses into acylglucoses, enabling specialized metabolic diversity.

bioRxiv · Dec 20, 2018Plant Biology