Author

O. Pines

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:E. coli· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

K. Das· 2 shared N. Lehming· 2 shared A. Hayashi· 1 shared A. Khatib· 1 shared A. Saada· 1 shared B. Solaimuthu· 1 shared D. Lintzer· 1 shared E. Singer· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

K. Das

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mitochondrial Derived Vesicles retain membrane potential and contain a functional ATP synthase

R. Hazan (Ben-Menachem), D. Lintzer, T. Ziv, K. Das, I. Rosenhek-Goldian, Z. Porat, H. Ben Ami Pilo, S. Karniely, A. Saada, N. Regev-Rudzki, O. Pines

The paper isolates and characterizes Mitochondrial Derived Vesicles (MDVs) from yeast, showing they contain functional ATP synthase and membrane potential, suggesting a role in organelle communication.

bioRxiv · Jul 10, 2022Cell Biology

Depletion of FH, an essential TCA cycle enzyme, drives proliferation in a two-step model

B. Solaimuthu, M. Lichtenstein, A. Hayashi, A. Khatib, I. Plaschkes, Y. Nevo, M. Tanna, S. Lavi, O. Pines, Y. D. Shaul

This study investigates how FH loss drives cell proliferation through adaptive mutations in oncogenic pathways despite initial DNA damage and growth inhibition.

bioRxiv · Jun 16, 2022 · PreprintCancer Biology

Ubiquitination occurs in the mitochondrial matrix byeclipsed targeted components of the ubiquitin machinery

Y. Zhang, O. Karmon, K. Das, M. Mark, N. Lehming, O. Pines

The paper demonstrates that ubiquitination occurs in yeast mitochondrial matrix using components of the ubiquitin machinery, independent of cytosolic proteasome activity.

bioRxiv · Apr 21, 2022Cell Biology

A novel combination of Class-I fumarases and metabolites (α-ketoglutarate and fumarate) signal the DNA damage response in E. coli.

Y. Silas, E. Singer, N. Lehming, O. Pines

This paper shows that in E. coli, Class-I fumarases participate in DNA damage repair through a novel signaling mechanism involving alpha-ketoglutarate and the enzyme AlkB.

bioRxiv · Aug 4, 2020 · PreprintMicrobiology