Author

O. R. Shamaa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Y. Meliton· 2 shared G. M. Mutlu· 2 shared K. A. Sun· 2 shared P. S. Woods· 2 shared R. B. Hamanaka· 2 shared R. Cetin-Atalay· 2 shared Y. Tian· 2 shared A. Muir· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

A. Y. Meliton

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Author profile →

2 papers

Recent·Most cited

Mitochondrial One-Carbon Metabolism is Required for TGF-β-Induced Glycine Synthesis and Collagen Protein Production

A. Y. Meliton, R. Cetin-Atalay, Y. Tian, J. C. Szafran, K. W. D. Shin, T. Cho, K. A. Sun, P. S. Woods, O. R. Shamaa, B. Chen, A. Muir, G. M. Mutlu, R. B. Hamanaka

This study shows that mitochondrial one-carbon metabolism is essential for TGF-β-induced glycine synthesis and collagen production in lung fibroblasts, suggesting MTHFD2 inhibitors could treat IPF.

bioRxiv · Nov 7, 2023Cell Biology

HIF-1α induces glycolytic reprogramming in tissue-resident alveolar macrophagesto promote survival during acute lung injury

P. S. Woods, L. M. Kimmig, K. A. Sun, A. Y. Meliton, O. R. Shamaa, Y. Tian, R. Cetin-Atalay, W. W. Sharp, R. B. Hamanaka, G. M. Mutlu

This study shows hypoxia stabilizes HIF-1α in alveolar macrophages, promoting glycolytic reprogramming that enhances survival during acute lung injury.

bioRxiv · Feb 28, 2022Cell Biology