Author

Oddgeir L. Holmen

Norwegian University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 3 Genetics· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 7 Approach:statistical model· 7 Research Focus:GWAS / association mapping· 6 Assay:GWAS summary statistics· 5 Assay:whole-genome sequencing· 2 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Kristian HveemiD· 5 shared Michael BoehnkeiD· 4 shared Chad M. BrummettiD· 3 shared Gonçalo R. AbecasisiD· 3 shared Hyun Min KangiD· 3 shared Anne Heidi SkogholtiD· 2 shared Bo JacobssoniD· 2 shared Brooke N. WolfordiD· 2 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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5 shared papersGenetics

Kristian HveemORCID

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Author profile →

7 papers

Recent·Most cited

GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets

Nick Dand, Philip E. Stuart, John Bowes, David Ellinghaus, Joanne Nititham, Jake R. Saklatvala, Maris Teder‐Laving, Laurent F. Thomas, Tanel Traks, Steffen Uebe, Gunter Assmann, David Baudry, Frank Behrens, Allison C. Billi, Matthew Arthur Brown, , James T. Elder

This study performs a GWAS meta-analysis of psoriasis, identifying 109 susceptibility loci, including 45 new ones, and highlights potential therapeutic targets and disease mechanisms.

Nature Communications · Feb 28, 2025Peer-reviewedGenetic & Genomic Medicine

Characterization of the genetic architecture of BMI in infancy and early childhood reveals age-specific effects and implicates pathways involved in Mendelian obesity

Øyvind Helgeland, Marc Vaudel, Pol Solé-Navais, Christopher J. Flatley, Julius Juodakis, Jonas Bačelis, Ingvild L. Koløen, Gun Peggy Knudsen, Bente Berg Johansson, Per Minor Magnus, Ted Reichborn‐Kjennerud, Pétur Benedikt Júlíusson, Camilla Stoltenberg, Oddgeir L. Holmen, Ole A. Andreassen, , Stefan Johansson

This study identifies 46 BMI loci in children aged 0-8 years, revealing age-specific effects and pathways linked to Mendelian obesity.

Nature Metabolism · Mar 21, 2022Peer-reviewedGenetic & Genomic Medicine

Random glucose GWAS in 493,036 individuals provides insights into diabetes pathophysiology, complications and treatment stratification

Vasiliki Lagou, Longda Jiang, Anna Ulrich, Liudmila Zudina, Karla Sofia Gutiérrez González, Zhanna Balkhiyarova, Alessia Faggian, Shiqian Chen, Petar V. Todorov, Sodbo Sharapov, Alessia David, Letizia Marullo, Reedik Mägi, Roxana‐Maria Rujan, Emma Ahlqvist, , Inga Prokopenko

This study performs a GWAS on random glucose measurements in 493,036 individuals, identifying 128 loci associated with glycaemic traits and providing insights into diabetes biology and treatment.

medRxiv · Apr 17, 2021 · PreprintGenetic & Genomic Medicine

Genome-wide association study reveals a dynamic role of common genetic variation in infant and early childhood growth

Øyvind Helgeland, Marc Vaudel, Pétur Benedikt Júlíusson, Oddgeir L. Holmen, Julius Juodakis, Jonas Bačelis, Bo Jacobsson, Haakon Lindekleiv, Kristian Hveem, Rolv Terje Lie, Gun Peggy Knudsen, Camilla Stoltenberg, Per Minor Magnus, Jørn Vegard Sagen, Anders Molven, , Pål R. Njølstad

This study identifies five BMI-associated loci across 12 time points in children, highlighting transient effects of common genetic variation in the leptin signaling pathway during infancy.

Nature Communications · Oct 1, 2019Peer-reviewedGenetics

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

Jonas Bille Nielsen, Oren Rom, Ida L. Surakka, Sarah E. Graham, Wei Zhou, Lars G. Fritsche, Sarah A. Gagliano Taliun, Carlo Sidore, Yuhao Liu, Maiken Elvestad Gabrielsen, Anne Heidi Skogholt, Brooke N. Wolford, William Overton, Whitney Hornsby, Akua Acheampong, , Y. Eugene Chen

The paper identifies loss-of-function variants affecting liver-related blood traits that reduce CVD risk without increasing metabolic disease risk, highlighting potential therapeutic targets.

bioRxiv · Apr 2, 2019 · PreprintGenomics

Genome-wide association study of 1 million people identifies 111 loci for atrial fibrillation

Jonas Bille Nielsen, Rósa B. Þórólfsdóttir, Lars G. Fritsche, Wei Zhou, Morten Wagner Skov, Sarah E. Graham, Todd J. Herron, Shane McCarthy, Ellen M. Schmidt, Garðar Sveinbjörnsson, Ida L. Surakka, Michael R. Mathis, Masatoshi Yamazaki, Ryan Crawford, Maiken Elvestad Gabrielsen, , Cristen J. Willer

This study identifies 111 genetic loci and 163 risk variants associated with atrial fibrillation using a GWAS of over 1 million individuals.

Nature Genetics · Jul 26, 2018Peer-reviewedGenetics

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

Luke M. Evans, Rasool Tahmasbi, Matthew Jones, Scott I. Vrieze, Gonçalo R. Abecasis, Sayantan Das, Douglas W. Bjelland, Teresa R de Candia, David Altshuler, Carl A. Anderson, Andrea Angius, Jeffrey C. Barrett, Sonja I. Berndt, Michael Boehnke, Dorrett Boomsma, , George Davey Smith

This paper estimates narrow-sense heritability using identity-by-descent information in unrelated individuals and finds that IBD-based methods can capture rare variant contributions but are affected by stratification.

Heredity · Mar 28, 2018Peer-reviewedGenetics