Author

P. A. Barry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 3 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:rat· 4 Research Focus:clustering· 2 Organism:non-human primate· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Kaur· 5 shared S. R. Permar· 4 shared D. Malouli· 3 shared H. Taher· 3 shared S. G. Hansen· 3 shared A. Mirza· 2 shared C. Chan· 2 shared C. E. Otero· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersMicrobiology

A. Kaur

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Relationship of maternal cytomegalovirus-specific antibody responses and viral load to vertical transmission risk following primary maternal infection in a rhesus macaque model

C. E. Otero, R. Barfield, E. Scheef, C. S. Nelson, N. Rodgers, H.-Y. Wang, M. Moström, T. D. Manuel, J. Sass, K. Schmidt, H. Taher, C. Papen, L. Sprehe, S. Kendall, A. Davalos, , S. R. Permar

This study investigates maternal cytomegalovirus (CMV) antibody responses and viral load in rhesus macaques to determine their association with vertical transmission risk, finding no link between plasma viremia or humoral responses and congenital CMV in immunocompetent dams.

PLOS Pathogens · Oct 23, 2023Peer-reviewedImmunology

The pentameric complex is not required for vertical transmission of cytomegalovirus in seronegative pregnant rhesus macaques

H.-Y. Wang, H. Taher, C. N. Kreklywich, K. A. Schmidt, E. A. Scheef, R. Barfield, C. E. Otero, S. Valencia, C. M. Crooks, A. Mirza, K. Woods, N. V. Burgt, T. F. Kowalik, P. A. Barry, S. G. Hansen, , D. Malouli

The study shows that deleting the pentameric complex in rhesus CMV does not affect congenital transmission in seronegative pregnant rhesus macaques.

bioRxiv · Jun 15, 2023 · PreprintMicrobiology

Protective effect of pre-existing natural immunity in a nonhuman primate reinfection model of congenital cytomegalovirus infection

M. J. Mostrom, S. Yu, D. Tran, F. Saccoccio, C. J. Versoza, D. J. Malouli, A. Mirza, S. Valencia, M. Gilbert, R. V. Blair, S. G. Hansen, P. A. Barry, K. Fruh, J. D. Jensen, S. P. Pfeifer, , A. Kaur

This study shows that pre-existing CMV immunity in nonhuman primates reduces placental transmission and fetal loss during reinfection compared to primary infection.

bioRxiv · Apr 10, 2023 · PreprintImmunology

FcRγ- NK cell induction by specific CMV and expansion by subclinical viral infections in rhesus macaques

J. Lee, W. Chang, J. M. Scott, S. Hong, T. Lee, J. D. Deere, P. Park, E. E. Sparger, S. Dandekar, D. Hartigan-O'Connor, P. A. Barry, S. Kim

This study identifies RhCMV-specific induction of FcRγ-deficient NK cells in rhesus macaques, with co-infections enhancing their frequency.

bioRxiv · May 26, 2022 · PreprintImmunology

In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome

H. Taher, E. Mahyari, C. Kreklywich, L. S. Uebelhoer, M. R. McArdle, M. J. Moström, A. Bhusari, M. Nekorchuk, T. Whitmer, E. A. Scheef, L. M. Sprehe, D. Roberts, C. M. Hughes, K. A. Jackson, A. N. Selseth, , D. Malouli

This paper constructs a full-length rhesus cytomegalovirus (RhCMV) by repairing mutations in the 68-1 strain and shows it replicates more effectively in vivo compared to the passaged strain.

bioRxiv · Jun 2, 2020Microbiology

Bridging the gap: Using reservoir ecology and human serosurveys to estimate Lassa virus spillover in West Africa

A. J. Basinski, E. J. Fichet-Calvet, A. R. Sjodin, T. J. Varrelman, C. Remien, N. C. Layman, B. H. Bird, D. J. Wolking, C. Monagin, B. M. Ghersi, P. A. Barry, M. A. Jarvis, P. E. Gessler, S. L. Nuismer

This paper develops a machine learning framework to estimate Lassa virus spillover risk by separating reservoir and spillover risk components, finding Nigeria accounts for over half of annual infections.

bioRxiv · Mar 5, 2020Ecology

Impact of preexisting virus-specific maternal antibodies on cytomegalovirus population genetics in a monkey model of congenital transmission

D. Vera Cruz, C. S. Nelson, D. Tran, P. A. Barry, A. Kaur, K. Koelle, S. R. Permar

This study examines how maternal antibodies affect CMV genetic diversity in a monkey model, finding no impact on viral genetic diversity despite reduced viral load and congenital transmission.

bioRxiv · Jul 20, 2019Microbiology