D. Lawson

A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

This study identifies tonic activation of the cGAS-STING and IFN pathways in ACE2-positive airway cells as a factor limiting SARS-CoV-2 replication.

Fine-tuning of Epithelial EGFR signals Supports Coordinated Mammary Gland Development

This study shows that Rasgrp1 fine-tunes EGFR signals in mammary epithelial cells to regulate development during puberty, with in vitro and in vivo effects on proliferation, branching, and cellularity.

Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis

This study identifies three mechanisms by which class II HIV-1 integrase substitutions disrupt IN-RNA interactions, leading to virion maturation defects and premature viral genome degradation.

Minimum Information for Reusable Arthropod Abundance Data (MIReAAD)

The paper introduces MIReAAD, a framework for standardizing arthropod abundance data to improve reusability and comparability across studies.

Uncoupled activation and cyclisation in catmint reductive terpenoid biosynthesis

The paper identifies NEPS enzymes in catmint that catalyse stereoselective cyclisation of an enol intermediate into nepetalactol isomers, revealing uncoupled activation and cyclisation in reductive terpenoid biosynthesis.

RADpainter and fineRADstructure: population inference from RADseq data

The paper introduces RADpainter and fineRADstructure to infer population structure from RADseq data, demonstrating their effectiveness with example datasets.