P. D. Dixit

GENERALIST: An efficient generative model for protein sequence families

The paper introduces GENERALIST, a generative model for protein sequence families that accurately captures amino acid covariation and predicts stable sequences.

Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited

This study shows that cancer cells rely on environmental lipids for proliferation under conditions of limited electron acceptors, such as hypoxia or mitochondrial inhibition.

Reverse plasticity underlies rapid evolution by clonal selection within populations of fibroblastspropagated on a novel soft substrate

This study shows that reverse plasticity drives rapid evolution in fibroblasts adapted to soft substrates through genetic changes, not phenotypic plasticity alone.

Macroecological dynamics of gut microbiota

The paper identifies scaling relationships in gut microbiota dynamics across humans and mice, showing similarities to ecological and economic systems and revealing effects of diet and environment.

Quantifying spatiotemporal dynamics and noise in absolute microbiota abundances using replicate sampling

The paper introduces DIVERS, a method to quantify spatiotemporal dynamics and noise in microbiota abundances using replicate sampling and spike-in sequencing, applied to the human gut microbiome.