S. Chakrabarty

Molecular Mechanism of Regulation of RhoA GTPase by Phosphorylation of RhoGDI

This study investigates how phosphorylation of RhoGDI regulates RhoA GTPase activation through molecular dynamics simulations and binding free energy calculations.

MiR-4521 perturbs FOXM1-mediated DNA damage response in breast cancer

This study shows miR-4521 targets FOXM1, reducing its expression and impairing DNA damage response, leading to increased cell death and reduced proliferation in breast cancer cells.

Anti-Biofilm Potential of Nanonized Eugenol against Pseudomonas aeruginosa

This study develops eugenol nanoparticles (ENPs) that show enhanced anti-biofilm activity against Pseudomonas aeruginosa compared to bulk eugenol.

Genetic diversity analysis and characterization of Ugandan sorghum

This study characterizes Ugandan sorghum genetic diversity using whole genome SNPs and identifies genomic regions associated with juvenile cold tolerance for breeding improvement.

Loss of Nuclear DNA Ligase III Reverts PARP Inhibitor Resistance in BRCA1/53BP1 Double-deficient Cells by Exposing ssDNA Gaps

This study identifies loss of LIG3 as a factor that reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by increasing ssDNA gaps.

Quantitative estimates of deciduousness in woody species from a seasonally dry tropical forest are related to leaf functional traits and the timing of leaf flush

The paper quantifies continuous variation in deciduousness among woody species in a seasonally dry tropical forest and links it to leaf traits and leaf flush timing.

Structural and dynamical heterogeneity of water trapped inside Na+-pumping KR2 rhodopsin in the dark state

The paper investigates water dynamics in KR2 rhodopsin's dark state using MD simulations, revealing structural and dynamical heterogeneity in water pockets and their interactions with protein residues.