Author

P. H. Seeberger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Pharmacology & Toxicology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:drug response / drug discovery· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:metabolomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

D. Kolarich· 2 shared J. Trimpert· 2 shared K. Alagesan· 2 shared K. Gilmore· 2 shared A. Everest-Dass· 1 shared A. Freitag· 1 shared A. K. Menon· 1 shared A. Offersgaard· 1 shared

Activity by Year

2019-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersBiochemistry

D. Kolarich

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Thiol-mediated Uptake of a Cysteine-containing Nanobody for Anti-Cancer Drug Delivery

F. Goerdeler, E. E. Reuber, J. Luehle, S. Leichnitz, A. Freitag, R. Nedielkov, H. M. Moeller, P. H. Seeberger, O. Moscovitz

This paper describes a nanobody that binds and internalizes into B cell lymphoma via thiol interactions, enabling drug delivery and diagnostic applications.

bioRxiv · Jul 12, 2022 · PreprintCancer Biology

Better together - Relative retention time plus spectral matching improves automated glycan characterization using PGC-nLC-IT-ESI-MS/MS

K. Alagesan, F. Schirmeister, U. Moeginger, A. Everest-Dass, F. Altmann, P. H. Seeberger, M. von Itzstein, N. H. Packer, D. Kolarich

The paper introduces GlycoRRT, a tool combining retention time and spectral analysis for automated glycan characterization using PGC-nLC-MS/MS, and applies it to human and animal glycomics data.

bioRxiv · Aug 4, 2021 · PreprintBiochemistry

A semisynthetic glycoconjugate provides expanded cross-serotype protection against Streptococcus pneumoniae

P. M. Kaplonek, L. Yao, K. Reppe, F. M. Voss, T. Kohler, F. Ebner, A. Schaefer, U. Blohm, P. Priegue, M. Brautigam, C. L. Pereira, S. G. Parameswarappa, M. Emmadi, P. Menova, M. Witzenrath, , P. H. Seeberger

This paper develops a synthetic glycoconjugate vaccine that combines pneumococcal proteins with a defined oligosaccharide to provide broad protection against multiple serotypes of Streptococcus pneumoniae in animal models.

bioRxiv · Jul 29, 2021Immunology

CLPTM1L is a lipid scramblase involved in glycosylphosphatidylinositol biosynthesis

Y. Wang, A. K. Menon, Y. Maki, Y.-S. Liu, Y. Iwasaki, M. Fujita, P. A. Guerrero, D. V. Silva, P. H. Seeberger, Y. Murakami, T. Kinoshita

The paper identifies CLPTM1L as a lipid scramblase essential for translocating glucosaminyl-phosphatidylinositol across the ER membrane during GPI biosynthesis.

bioRxiv · Jul 12, 2021 · PreprintBiochemistry

In vitro efficacy of Artemisia extracts against SARS-CoV-2

C. Nie, J. Trimpert, S. Moon, R. Haag, K. Gilmore, B. B. Kaufer, P. H. Seeberger

This study evaluates the in vitro antiviral efficacy of Artemisia extracts and a herbal drink against SARS-CoV-2 and FCoV, showing inhibition at non-toxic concentrations.

bioRxiv · Feb 14, 2021Pharmacology & Toxicology

In vitro efficacy of Artemisinin-based treatments against SARS-CoV-2

K. Gilmore, Y. Zhou, S. Ramirez, L. V. Pham, U. Fahnoe, S. Feng, A. Offersgaard, J. Trimpert, J. Bukh, K. Osterrieder, J. Gottwein, P. H. Seeberger

This study evaluates the in vitro antiviral efficacy of Artemisia annua extracts and artemisinin derivatives against SARS-CoV-2, finding artesunate to be the most potent.

bioRxiv · Oct 5, 2020 · PreprintPharmacology & Toxicology

A novel, ultrasensitive approach for quantitative carbohydrate composition and linkage analysis using LC-ESI ion trap tandem mass spectrometry

K. Alagesan, D. Varon Silva, P. H. Seeberger, D. Kolarich

This paper introduces a sensitive method for quantifying and analyzing carbohydrate composition and linkages using LC-ESI-MS/MS with permethylation and reductive amination steps.

bioRxiv · Nov 24, 2019 · PreprintBiochemistry