Author

M. von Itzstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Van Den Bergh· 2 shared P. Guillon· 2 shared A. Calcutt· 1 shared A. Everest-Dass· 1 shared B. Bailly· 1 shared C. Trappetti· 1 shared D. Grice· 1 shared D. Kolarich· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Van Den Bergh

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Drug repurposing for therapeutic discovery against human metapneumovirus infection

A. Van Den Bergh, P. Guillon, M. von Itzstein, B. Bailly, L. Dirr

This study identifies potential anti-HMPV drug candidates through medium-throughput screening, finding mycophenolic acid as a promising repurposed drug with low in vitro cytotoxicity.

bioRxiv · Jul 24, 2022Pharmacology & Toxicology

A phasevarion controls multiple virulence traits, including expression of vaccine candidates, in Streptococcus pneumoniae

Z. N. Phillips, C. Trappetti, A. Van Den Bergh, G. Martin, A. Calcutt, V. Ozberk, P. Guillon, M. Pandey, M. von Itzstein, W. E. Swords, J. C. Paton, M. P. Jennings, J. M. Atack

This study shows that the SpnIII phasevarion in S. pneumoniae affects multiple virulence traits and vaccine candidate expression, highlighting its importance in vaccine design.

bioRxiv · Feb 8, 2022 · PreprintMicrobiology

Overcoming microenvironment-mediated chemoprotection through stromal Galectin-3 inhibition in acute lymphoblastic leukemia

N. Heisterkamp, S. S. Tarighat, F. Fei, E. j. Joo, H. Abdel-Azim, K. Bum-Erdene, D. Grice, H. Blanchard, M. von Itzstein, H. Geng, L. Yang

This study shows that inhibiting stromal Galectin-3 enhances chemotherapy effectiveness in BCP-ALL by disrupting leukemia cell migration, adhesion, and drug resistance.

bioRxiv · Sep 24, 2021Cancer Biology

Better together - Relative retention time plus spectral matching improves automated glycan characterization using PGC-nLC-IT-ESI-MS/MS

K. Alagesan, F. Schirmeister, U. Moeginger, A. Everest-Dass, F. Altmann, P. H. Seeberger, M. von Itzstein, N. H. Packer, D. Kolarich

The paper introduces GlycoRRT, a tool combining retention time and spectral analysis for automated glycan characterization using PGC-nLC-MS/MS, and applies it to human and animal glycomics data.

bioRxiv · Aug 4, 2021 · PreprintBiochemistry