Author

Y. Iwasaki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Hamamoto· 1 shared A. K. Menon· 1 shared A. Kimura· 1 shared A. Suzuki· 1 shared D. V. Silva· 1 shared F. Takenoya· 1 shared H. Takatsu· 1 shared H.-W. Shin· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperCell Biology

A. Hamamoto

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Novel phosphatidylinositol flippases contribute to phosphoinositide homeostasis in the plasma membrane

Y. Muranaka, R. Shigetomi, Y. Iwasaki, A. Hamamoto, K. Nakayama, H. Takatsu, H.-W. Shin

This study identifies ATP8B1, ATP8B2, and ATP10A as phosphatidylinositol flippases that regulate plasma membrane phosphoinositide homeostasis by maintaining PtdIns(4,5)P2 levels.

bioRxiv · Jul 3, 2023Cell Biology

Immune cell multi-omics analysis reveals contribution of oxidative phosphorylation to B cell functions and organ damage of lupus

Y. Takeshima, Y. Iwasaki, M. Nakano, Y. Narushima, M. Ota, Y. Nagafuchi, S. Sumitomo, T. Okamura, K. B. Elkon, K. Ishigaki, A. Suzuki, Y. Kochi, K. Yamamoto, K. Fujio

The paper identifies oxidative phosphorylation (OXPHOS) as a key driver in SLE B cells, linking mitochondrial dysfunction to immune signaling and organ damage.

bioRxiv · Oct 8, 2021 · PreprintImmunology

CLPTM1L is a lipid scramblase involved in glycosylphosphatidylinositol biosynthesis

Y. Wang, A. K. Menon, Y. Maki, Y.-S. Liu, Y. Iwasaki, M. Fujita, P. A. Guerrero, D. V. Silva, P. H. Seeberger, Y. Murakami, T. Kinoshita

The paper identifies CLPTM1L as a lipid scramblase essential for translocating glucosaminyl-phosphatidylinositol across the ER membrane during GPI biosynthesis.

bioRxiv · Jul 12, 2021 · PreprintBiochemistry

Unsupervised explainable AI for simultaneous molecular evolutionary study of forty thousand SARS-CoV-2 genomes

T. Ikemura, K. Wada, Y. Wada, Y. Iwasaki, T. Abe

The paper applies an explainable AI method to analyze 40,000 SARS-CoV-2 genomes, revealing clade clustering based on oligonucleotide composition without prior knowledge.

bioRxiv · Oct 11, 2020 · PreprintEvolutionary Biology

Cold Vacuum Extracts of Double Cherry Blossom (Gosen-Sakura) Leaves Show Antitumor Activity

R. Rakwal, J. Shibato, F. Takenoya, T. Hirabayashi, A. Kimura, Y. Iwasaki, Y. Toyota, M. Hori, S. Tamogami, S. Shioda

This study extracts and tests compounds from Gosen-Sakura leaves, finding novel antitumor compounds that inhibit tumor cell proliferation.

bioRxiv · Feb 16, 2019 · PreprintPlant Biology