Author

P. Jacob

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Arabidopsis· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

J. L. Dangl· 2 shared Y. Yang· 2 shared A. Bayless· 1 shared B. J. McKinney· 1 shared C. R. Fitzpatrick· 1 shared D. Kwon· 1 shared D. Russ· 1 shared F. El-Kasmi· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPlant Biology

J. L. Dangl

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3 papers

Recent·Most cited

Broader functions of TIR domains in Arabidopsis immunity

P. Jacob, J. Hige, L. Song, A. Bayless, D. Russ, V. Bonardi, F. El-Kasmi, L. Wunsch, Y. Yang, C. R. Fitzpatrick, B. J. McKinney, M. T. Nishimura, M. R. Grant, J. L. Dangl

This study identifies SADR1 as a TIR-containing receptor that modulates RNL-driven immune signaling in Arabidopsis, revealing TIR domains' broader roles in immunity beyond EDS1-dependent pathways.

bioRxiv · Dec 23, 2022Plant Biology

Allelic variation in the Arabidopsis TNL CHS3/CSA1 immune receptor pair reveals two functional regulatory modes

Y. Yang, N. H. Kim, V. Cevik, P. Jacob, L. Wan, O. J. Furzer, J. L. Dangl

The paper identifies two regulatory modes in the Arabidopsis CHS3/CSA1 immune receptor pair, showing how an integrated domain (ID) in clade 1 CHS3 enables effector binding, while other clades rely on detecting effector-modified pattern recognition receptors.

bioRxiv · May 10, 2022 · PreprintPlant Biology

Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/ Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance.

D. Kwon, S.-m. Kim, P. Jacob, Y. Liu, M. A. Correia

This study shows that genetic ablation of gp78/AMFR in mice stabilizes hepatic P450 enzymes, enhancing their drug metabolism and potentially affecting drug response and toxicity.

Molecular Pharmacology · Nov 1, 2019Peer-reviewedPharmacology & Toxicology