Author

P. Jat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

J. Bieschke· 2 shared J. Collinge· 2 shared A. R. Clarke· 1 shared B. Caughey· 1 shared E. Dobrinskikh· 1 shared F. Sobott· 1 shared G. R. Nahass· 1 shared I. Benilova· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

J. Bieschke

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Author profile →

3 papers

Recent·Most cited

Alanine replacements in the structured C-terminal domain of the prion protein reveal conformationally variable regions as major determinants for prion propagation

S. K. Bhamra, P. Arora, L. L. P. Hosszu, J. Bieschke, A. R. Clarke, J. Collinge, P. Jat

This study uses alanine mutagenesis to identify conformationally variable regions in PrPC that are critical for prion propagation.

bioRxiv · Jan 19, 2023 · PreprintBiochemistry

Brazilin Removes Toxic alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium

G. R. Nahass, Y. Sun, Y. Xu, M. Batchelor, M. Reilly, I. Benilova, N. Kedia, K. Spehar, F. Sobott, R. B. Sessions, B. Caughey, S. E. Radford, P. Jat, J. Collinge, J. Bieschke

This paper shows Brazilin inhibits alpha-synuclein fibril formation and reduces toxicity in Parkinson's disease by altering conformational equilibrium.

bioRxiv · Sep 29, 2020Biochemistry

Differential trafficking of albumin and IgG facilitated by the neonatal Fc receptor in podocytes in vitro and in vivo.

J. Dylewski, E. Dobrinskikh, L. Lewis, P. Tonsawan, P. Jat, J. Blaine

This study investigates the role of FcRn in albumin and IgG trafficking in podocytes, finding differential effects on IgG accumulation in vitro and in vivo.

bioRxiv · Dec 12, 2018Cell Biology