Author

P. M. French

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

G. A. Rutter· 2 shared A. Inoue· 1 shared A. Martinez-Sanchez· 1 shared A. Oishi· 1 shared A. Tomas· 1 shared B. Jones· 1 shared C. Dunsby· 1 shared D. A. Jacobson· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

G. A. Rutter

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2 papers

Recent·Most cited

Signal bias at glucagon family receptors: rationale and downstream impacts

B. Jones, E. R. McGlone, Z. Fang, P. Pickford, I. R. Correa, A. Oishi, R. Jockers, A. Inoue, S. Kumar, F. Görlitz, C. Dunsby, P. M. French, G. A. Rutter, T. M. Tan, A. Tomas, S. R. Bloom

The paper investigates signal bias at glucagon family receptors, showing biased agonists affect intracellular signaling and insulin secretion differently.

bioRxiv · Apr 26, 2020Pharmacology & Toxicology

The mitochondrial Ca2+ uniporter MCU is required for normal glucose-stimulated insulin secretion in vitro and in vivo

E. Haythorne, E. Georgiadou, M. Dickerson, L. Lopez Noriega, T. J. Pullen, G. da Silva Xavier, S. Davis, A. Martinez-Sanchez, F. Semplici, R. Rizzuto, J. A. McGinty, P. M. French, M. C. Cane, D. A. Jacobson, I. Leclerc, G. A. Rutter

This study shows that the mitochondrial Ca2+ uniporter MCU is essential for normal glucose-stimulated insulin secretion in pancreatic beta-cells, both in vitro and in vivo.

bioRxiv · Sep 25, 2019Physiology