A. Oishi

Callose Deficiency Modulates Plasmodesmata frequency and the intercellular space In Rice Anthers

This study investigates the role of callose in modulating plasmodesmata frequency and intercellular spacing in rice anther cells during meiosis.

Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells

This paper develops tau biosensors using Nanoluciferase technology to monitor tau conformational changes and seeding activity in living cells, identifying potential therapeutic targets for tauopathies.

Acylation of the incretin peptide exendin-4 directly impacts GLP-1 receptor signalling and trafficking

This study compares exendin-4 and its acylated variant exendin-4-C16, showing acylation affects GLP-1R signaling bias, trafficking, and pharmacokinetics.

A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling

The paper identifies a novel endosomal recycling pathway in yeast and humans involving Mvp1/SNX8 and Vps1, distinct from retromer and Snx4 pathways.

Enterohepatic transcription factor CREB3L3 protects atherosclerosis via SREBP competitive inhibition

This study shows CREB3L3 protects against atherosclerosis by inhibiting SREBP activity through competitive antagonism, reducing lipogenic and cholesterogenic gene expression.

Signal bias at glucagon family receptors: rationale and downstream impacts

The paper investigates signal bias at glucagon family receptors, showing biased agonists affect intracellular signaling and insulin secretion differently.