A heterocyclic compound inhibits viral release by inducing cell surface BST2/Tetherin/CD317/HM1.24
P. Nyame, A. Togami, T. Yoshida, T. Masunaga, M. M. Begum, H. Terasawa, N. Monde, Y. Tahara, R. Tanaka, Y. Tanaka, J. A. Kubi, W. O. Amesimeku, M. J. Hossain, M. Otsuka, K. Yoshimura, , K. Monde
This paper identifies a heterocyclic compound, HT-7, that inhibits HIV-1 release by increasing cell surface BST2 expression with minimal cellular toxicity.
bioRxiv · May 3, 2024Microbiology