K. Yoshimura

Virological characteristics of the SARS-CoV-2 KP.2 variant

This study investigates the virological properties of the SARS-CoV-2 KP.2 variant, finding it has higher viral fitness and immune resistance compared to JN.1, contributing to its rapid spread.

A heterocyclic compound inhibits viral release by inducing cell surface BST2/Tetherin/CD317/HM1.24

This paper identifies a heterocyclic compound, HT-7, that inhibits HIV-1 release by increasing cell surface BST2 expression with minimal cellular toxicity.

Virological characteristics of the SARS-CoV-2 Omicron HK.3 variant harboring the "FLip" substitution

This study investigates the virological properties of the SARS-CoV-2 HK.3 variant, a FLip variant with substitutions S:L455F and S:F456L, to assess its growth advantage.

Virological characteristics of the SARS-CoV-2 BA.2.86 variant

This study investigates the virological characteristics of the SARS-CoV-2 BA.2.86 variant, finding it has higher reproduction number than EG.5.1 but lower pathogenicity and replication capacity compared to BA.2.

Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant

The paper investigates the virological features of the SARS-CoV-2 EG.5.1 variant, finding its fitness and antiviral sensitivity comparable to XBB.1.5, with structural differences in spike proteins.

Virological characteristics correlating with SARS-CoV-2 spike protein fusogenicity

This study examines virological parameters of SARS-CoV-2 variants correlating with spike protein fusogenicity, finding strong links with S1/S2 cleavage efficiency and plaque size.

AtDREB2G is a novel regulator of riboflavin biosynthesis under low-temperature stress and abscisic acid treatment in Arabidopsis thaliana

Antiviral efficacy of the SARS-CoV-2 XBB breakthrough infection sera against Omicron subvariants including EG.5

This study evaluates the antiviral efficacy of XBB breakthrough infection sera against EG.5.1 and other Omicron subvariants, finding comparable neutralization titers and suggesting immune evasion is not the main driver of EG.5.1's spread.

Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants

This study identifies XBB as a SARS-CoV-2 variant resulting from recombination of BA.2 subvariants, showing increased resistance to neutralizing antibodies and enhanced fusogenicity compared to BA.2.75.

Convergent evolution of the SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant

The paper investigates convergent evolution in SARS-CoV-2 Omicron subvariants, identifying five critical spike protein substitutions in BQ.1.1 that enhance viral fitness and antibody resistance.

Virological characteristics of the SARS-CoV-2 Omicron BA.2.75

This study investigates the virological characteristics of SARS-CoV-2 Omicron BA.2.75, finding it has higher transmissibility and pathogenicity compared to BA.2 and BA.5, but similar sensitivity to antiviral drugs.

Virological characteristics of the novel SARS-CoV-2 Omicron variants including BA.2.12.1, BA.4 and BA.5

This study analyzes the virological characteristics of SARS-CoV-2 Omicron variants BA.2.12.1, BA.4, and BA.5, finding they have higher reproduction numbers, reduced neutralization by prior immunity, increased replication in lung cells, and greater pathogenicity in hamsters compared to BA.2.

SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variant

This study identifies the S375F mutation in the Omicron spike protein as responsible for its reduced cleavage efficiency, fusogenicity, and rapid spread.

m6A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small cell lung cancer

Virological characteristics of SARS-CoV-2 BA.2 variant

This study compares the virological characteristics of SARS-CoV-2 BA.2 and BA.1 variants, finding BA.2 has higher transmissibility, different antigenicity, greater replicative capacity, and higher pathogenicity in hamsters.

A widely-distributed HIV-1 provirus elimination assay to evaluate latency-reversing agents in vitro

The paper develops a new assay to evaluate latency-reversing agents by eliminating HIV-1 proviruses in a long-term cell culture system.

SARS-CoV-2 spike P681R mutation, a hallmark of the Delta variant, enhances viral fusogenicity and pathogenicity

This study shows the P681R mutation in the SARS-CoV-2 spike protein enhances fusogenicity and pathogenicity in the Delta variant compared to the prototypic virus.

Discovery of the fastest myosin, its amino acid sequence, and structural features

The paper identifies CbXI-1 as the fastest myosin with a velocity of 73 m s-1, cloned from Chara braunii, and reports its atomic structure and structural features contributing to high-speed movement.

Basis for the phototaxis sign reversal in the green alga Chlamydomonas reinhardtii studied by high-speed observation

This study identifies two factors determining phototactic sign reversal in Chlamydomonas reinhardtii through high-speed observation and a mathematical model.

\"Low-cost\" initial burst of root development in whole Fagus crenata seedlings: The key to survival?

The paper measures metabolic rates and growth in Fagus crenata seedlings to show roots develop more rapidly and efficiently than other organs, supporting seedling survival.