Author

P. Perez-Pinera

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Organism:mouse· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

T. Gaj· 2 shared A. Miskalis· 1 shared A. Nambiar· 1 shared A. Zeballos· 1 shared C. K. W. Lim· 1 shared C. Saporito-Magrina· 1 shared D. Swami· 1 shared G. D. McPheron· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

T. Gaj

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

SPLICER: A Highly Efficient Base Editing Toolbox That Enables In Vivo Therapeutic Exon Skipping

A. Miskalis, S. Shirguppe, J. Winter, G. Elias, D. Swami, A. Nambiar, M. Stilger, W. Woods, N. Gosstola, M. Gapinske, A. Zeballos, H. Moore, S. Maslov, T. Gaj, P. Perez-Pinera

SPLICER improves exon skipping by editing both splice acceptor and donor sites, reducing aberrant splicing and enabling therapeutic applications in Alzheimer's disease.

bioRxiv · Apr 1, 2024 · PreprintBioengineering

CRISPR base editing of cis-regulatory elements enables target gene perturbations

C. K. W. Lim, T. X. McCallister, C. Saporito-Magrina, G. D. McPheron, R. Krishnan, M. A. Zeballos, J. E. Powell, L. V. Clark, P. Perez-Pinera, T. Gaj

This study shows CRISPR base editors can reduce gene expression by editing cis-regulatory elements, with examples in human and mouse models.

bioRxiv · May 26, 2022 · PreprintBioengineering