Author

P. R. McDonald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Roy· 2 shared D. K. Johnson· 2 shared A. R. Fehr· 1 shared C. M. Kerr· 1 shared C. Y. Ly· 1 shared C. Yu· 1 shared D. J. Davido· 1 shared J. J. O'Connor· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

A. Roy

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Author profile →

2 papers

Recent·Most cited

Mutation of a highly conserved isoleucine residue in loop 2 of several ????-coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental to infection

C. M. Kerr, J. J. Pfannenstiel, Y. M. Alhammad, J. J. O'Connor, R. Ghimire, R. Shrestha, R. Khattabi, P. Saenjamsai, S. Parthasarathy, P. R. McDonald, P. Gao, D. K. Johnson, S. More, A. Roy, R. Channappanavar, A. R. Fehr

This study shows that mutating a conserved isoleucine in the macrodomain of MERS-CoV and SARS-CoV-2 enhances ADP-ribose binding but reduces viral replication and pathogenesis.

bioRxiv · Jan 3, 2024 · PreprintMicrobiology

Simple and Rapid High-Throughput Assay to Identify HSV-1 ICP0 Transactivation Inhibitors

C. Y. Ly, C. Yu, P. R. McDonald, A. Roy, D. K. Johnson, D. J. Davido

This paper develops a high-throughput assay to identify inhibitors of HSV-1 ICP0 transactivation, identifying 76 potential inhibitors from 19,000 compounds.

bioRxiv · Jan 13, 2021Microbiology