Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
C. J. Otter, N. Bracci, N. A. Parenti…·S. R. Weiss
This study shows that SARS-CoV-2 nsp15 inhibits dsRNA-induced antiviral signaling, which is necessary for viral replication in nasal epithelial cultures.
C. M. Kerr, J. J. Pfannenstiel, Y. M. Alhammad…·A. R. Fehr
This study shows that mutating a conserved isoleucine in the macrodomain of MERS-CoV and SARS-CoV-2 enhances ADP-ribose binding but reduces viral replication and pathogenesis.
S. Wazir, T. A. O. Parviainen, M. M. Maksimainen…·L. Lehtiö
This paper identifies small molecule inhibitors of SARS-CoV-2 Mac1 that inhibit coronavirus replication, validating Mac1 as an anti-viral target.
Y. M. Alhammad, S. Parthasarathy, R. Ghimire…·A. Fehr
This study shows that SARS-CoV-2 Mac1 is essential for pathogenesis but not replication, as Mac1-deleted virus replicates normally but induces higher IFN responses and reduced disease in mice.