Author

K. Kelley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:cryo-EM· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

B. Carragher· 2 shared E. T. Eng· 2 shared M. Kopylov· 2 shared A. Bartolomucci· 1 shared A. Frontini· 1 shared A. J. Noble· 1 shared A. M. Raczkowski· 1 shared B. S. Sahu· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

B. Carragher

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Children Who Develop Celiac Disease Exhibit Distinct Metabolic Pathways Among Their Gut Microbiota Years Before Diagnosis

K. Kelley, D. Dogru, Q. Huang, Y. Yang, N. Palm, J. Ludvigsson, E. ALTINDIS

bioRxiv · Jun 13, 2024 · PreprintMicrobiology

Prostaglandins as Candidate Ligands for a Per-ARNT-Sim (PAS) Domain of Steroid Receptor Coactivator 1 (SRC1)

N. Daffern, K. Kelley, J. Villegas, I. Radhakrishnan

The paper identifies prostaglandins as potential ligands for the PAS-B domain of SRC1, showing both non-covalent and covalent binding modes.

bioRxiv · Jul 13, 2023 · PreprintBiochemistry

Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis

B. S. Sahu, M. Razzoli, S. McGonigle, J. P. Pallais, M. Nguyen, M. Sadahiro, C. Jiang, W.-J. Lin, K. Kelley, P. Rodriguez, R. Mansk, C. Cero, G. Caviola, P. Palanza, L. Rao, , A. Bartolomucci

This study creates a mouse model with a selective knockout of the TLQP-21 neuropeptide, revealing its role in temperature-dependent resistance to diet-induced obesity and brown adipose tissue activation.

bioRxiv · Mar 23, 2023Physiology

Waffle Method: A general and flexible approach for FIB-milling small and anisotropically oriented samples

K. Kelley, A. M. Raczkowski, O. Klykov, P. Jaroenlak, D. Bobe, M. Kopylov, E. T. Eng, G. Bhabha, C. S. Potter, B. Carragher, A. J. Noble

The paper introduces the Waffle Method to improve cryo-FIB/SEM workflows for preparing complex biological samples for cryo-ET, demonstrating its effectiveness with various samples and hardware.

bioRxiv · Oct 28, 2020Microbiology

The impact of data reduction and lossy image formats on electron microscope images

E. T. Eng, M. Kopylov, C. J. Negro, S. Dallaykan, W. J. Rice, K. D. Jordan, K. Kelley, B. Carragher, C. Potter

This study examines how data compression and lossy image formats affect cryoEM reconstruction quality, finding that compressed data can still yield sub-2Å reconstructions.

bioRxiv · Oct 24, 2018 · PreprintBiophysics

MicroRNA-451a regulates colorectal cancer radiosensitivity

R. Ruhl, S. Rana, K. Kelley, C. Espinosa-Diez, C. Hudson, C. Lanciault, C. Thomas, L. V. Tsikitis, S. Anand

This study identifies miR-451a as a regulator of colorectal cancer radiosensitivity, showing it inhibits proliferation and enhances radiation response.

bioRxiv · May 9, 2017Cancer Biology